Current views on the pathogenesis of Sjögren's syndrome

E Pontarini, D Lucchesi… - Current opinion in …, 2018 - journals.lww.com
Advances in the understanding of pSS pathogenesis have paved the way for clinical trials
with novel biologic agents targeting immune pathways regulating T/B-cell interactions and …

Update on the immunobiology of Sjögren's syndrome

A Ambrosi, M Wahren-Herlenius - Current Opinion in …, 2015 - journals.lww.com
Progress made during the last few years on the pathogenesis of pSS has been mirrored by
clinical trials directed at inhibiting cytokines, B, or T cell responses. Future efforts should …

Update on the pathophysiology and treatment of primary Sjögren syndrome

C Baldini, G Fulvio, G La Rocca, F Ferro - Nature Reviews …, 2024 - nature.com
Sjögren syndrome or Sjögren disease is a chronic form of autoimmune epithelitis
characterized by lymphocytic infiltration of the exocrine glands, particularly the salivary and …

[PDF][PDF] Pathogenesis of primary Sjögren's syndrome beyond B lymphocytes

S Fasano, D Mauro, F Macaluso, F Xiao… - Clin Exp …, 2020 - clinexprheumatol.org
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder affecting exocrine
glands of the body, prevalently lacrimal and salivary glands. The pSS pathogenesis has …

New concepts in the pathogenesis of Sjögren syndrome: many questions, fewer answers

A Hansen, PE Lipsky, T Dörner - Current opinion in rheumatology, 2003 - journals.lww.com
Abstract Although a modified European–American consensus classification of Sjögren
syndrome has been introduced during the last year, the etiopathogenesis of this disease …

Treatment of primary Sjögren syndrome

A Saraux, JO Pers… - Nature Reviews …, 2016 - nature.com
Primary Sjögren syndrome (pSS) is a progressive autoimmune disease characterized by
sicca and systemic manifestations. In this Review, we summarize the available data on …

Pathogenesis of Sjögren's syndrome and therapeutic consequences

X Mariette, JE Gottenberg - Current opinion in rheumatology, 2010 - journals.lww.com
Pathogenesis of Sjögren's syndrome and therapeutic consequen... : Current Opinion in
Rheumatology Pathogenesis of Sjögren's syndrome and therapeutic consequences : Current …

B cells in the pathogenesis of primary Sjögren syndrome

G Nocturne, X Mariette - Nature Reviews Rheumatology, 2018 - nature.com
Primary Sjögren syndrome (pSS) is a prototypical autoimmune disease. The involvement of
B cells in the pathogenesis of pSS has long been suspected on the basis of clinical …

Treating the underlying pathophysiology of primary Sjögren syndrome: recent advances and future prospects

P Brito-Zerón, S Retamozo, H Gheitasi… - Drugs, 2016 - Springer
Sjögren Syndrome (SS) is a systemic autoimmune disease with a wide clinical spectrum that
extends from sicca symptoms of the mucosal surfaces to extra-glandular systemic …

Immunopathogenesis of primary Sjögren's syndrome: implications for disease management and therapy

A Hansen, PE Lipsky, T Dörner - Current opinion in rheumatology, 2005 - journals.lww.com
The pathogenesis of primary Sjögren's syndrome is complex and the factors initiating and
driving autoimmunity in this entity are largely unknown. Recent studies provide new insights …