Orbitofrontal cortex (OFC) neurons encode rewards and the cues that predict them,
providing a neural substrate for outcome expectancy, an important component of goal …

Memory can inform goal-directed behavior by linking current opportunities to past outcomes.
The orbitofrontal cortex (OFC) may guide value-based responses by integrating the history …

Anatomical, imaging, and lesion work have suggested that medial and lateral aspects of
orbitofrontal cortex (OFC) play different roles in reward-guided decision-making, yet few …

Research using laboratory animals, alongside clinical studies of human patients, support a
role for the orbitofrontal cortex (OFC) in adaptive decision‐making and goal‐directed …

The orbitofrontal cortex (OFC) has long been implicated in signaling information about
expected outcomes to facilitate adaptive or flexible behavior. Current proposals focus on …

Neurons in the orbitofrontal cortex (OFC) fire in anticipation of and during rewards. Such
firing has been suggested to encode reward predictions and to account in some way for the …

Animals can categorize the environment into “states,” defined by unique sets of available
action-outcome contingencies in different contexts. Doing so helps them choose appropriate …

The orbitofrontal cortex (OFC) has been described as signaling outcome expectancies or
value. Evidence for the latter comes from the studies showing that neural signals in the OFC …

Adaptive execution and inhibition of behavior are guided by the activity of neuronal
populations across multiple frontal cortical areas. The rodent medial prefrontal cortex has …

Certain goal-directed behaviors depend critically upon interactions between orbitofrontal
cortex (OFC) and basolateral amygdala (ABL). Here we describe direct neurophysiological …