Huntington's disease (HD) is a progressive neurodegenerative disease striking principally
medium spiny GABAergic neurons of the caudate nucleus of the basal ganglia. It affects …

Huntingtin expression was examined by Western blot and immunoprecipitation studies of
lymphoblastoid cell lines from Huntington's disease (HD) homozygotes, heterozygotes, and …

Huntington's disease (HD) is an autosomal, dominantly inherited neurodegenerative
disorder that is characterized by abnormal involuntary movements (chorea), intellectual …

Huntington's disease (HD) is an inherited neurodegenerative disorder that affects about one
in 10,000 individuals in North America. The genetic defect responsible for the disease is an …

Huntingtin is the protein involved in Huntington disease (HD), an inherited
neurodegenerative disease. Research activities have focused on the abnormal functions of …

Huntington disease (HD) is a devastating neurodegenerative disease that derives from CAG
repeat expansion in the huntingtin gene. The clinical syndrome consists of progressive …

This chapter reviews the neuropathology of Huntington's disease (HD) and examines the
relationships between the neurodegenerative findings and recent advances in our …

Huntington disease is an inherited neurodegeneration, for which the associated mutation
was isolated in 1993. The mutation is an expansion of a CAG trinucleotide repeat, which …

Of the neurodegenerative diseases presented in this book, Huntington's disease (HD)
stands as the archetypal autosomal dominantly inherited neurodegenerative disorder. Its …

Publisher Summary Huntington's disease (HD) is an autosomal dominant
neurodegenerative disorder characterized by movement disorders, cognitive deterioration …