Synergistic effects of combined therapy of curcumin and Fructus Ligustri Lucidi for treatment of osteoporosis: cellular and molecular evidence of enhanced bone …

SNA Bukhari, F Hussain, HE Thu, Z Hussain - Journal of integrative …, 2019 - Elsevier
Objective The present study explored the effects of the combined herbal therapy consisting
of curcumin (CUR) and Fructus Ligustri Lucidi (FLL) on aspects of bone regeneration …

[HTML][HTML] High water-soluble curcuminoids-rich extract regulates osteogenic differentiation of MC3T3-E1 cells: Involvement of Wnt/β-catenin and BMP signaling …

Y Pengjam, N Syazwani, J Inchai, A Numit… - Chinese Herbal …, 2021 - Elsevier
Objective The present study aimed to evaluate the effect of a high water-soluble
curcuminoids-rich extract (CRE) in a solid dispersion form (CRE-SD) using …

The potential therapeutic role of curcumin in osteoporosis treatment: based on multiple signaling pathways

K Wang - Frontiers in Pharmacology, 2024 - frontiersin.org
Osteoporosis is a common chronic metabolic bone disease caused by disturbances in
normal bone metabolism and an imbalance between osteoblasts and osteoclasts …

Fructus Ligustri Lucidi preserves bone quality through induction of canonical Wnt/β‐catenin signaling pathway in ovariectomized rats

H Liu, Y Guo, R Zhu, L Wang, B Chen… - Phytotherapy …, 2021 - Wiley Online Library
Fructus Ligustri Lucidi (FLL) has been preclinically and clinically used to treat
musculoskeletal diseases. However, whether and how FLL affect the canonical Wnt/β …

The impact of curcumin on bone osteogenic promotion of MC3T3 cells under high glucose conditions and enhanced bone formation in diabetic mice

J He, X Yang, F Liu, D Li, B Zheng, AO Abdullah, Y Liu - Coatings, 2020 - mdpi.com
Diabetic osteoporosis (DOP) is characterized by impaired bone microstructure and reduced
bone density resulting from high glucose levels. Curcumin (CURC) is extensively applied in …

[HTML][HTML] Extract of Curculigo capitulata Ameliorates Postmenopausal Osteoporosis by Promoting Osteoblast Proliferation and Differentiation

Y Wang, X Wang, K Wang, W Qin, N Li - Cells, 2024 - mdpi.com
Postmenopausal osteoporosis (PMOP) is a bone disease characterized by bone thinning
and an increased risk of fractures due to estrogen deficiency. Current PMOP therapies often …

Protective effects of curcumin against osteoporosis and its molecular mechanisms: a recent review in preclinical trials

S Yang, Y Sun, L Kapilevich, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Osteoporosis (OP) is one of the most common metabolic skeletal disorders and is commonly
seen in the elderly population and postmenopausal women. It is mainly associated with …

Effect and mechanism of curcumin on bone loss and osteoporosis: a systematic review

SH Ghahfarrokhi, S Heidari-Soureshjani… - Current Traditional …, 2023 - ingentaconnect.com
Background: Curcumin has been used in various diseases due to its potent anti-oxidant and
anti-inflammatory properties. Objective: This systematic review aims to investigate the effect …

[HTML][HTML] Combination therapy of curcumin and alendronate modulates bone turnover markers and enhances bone mineral density in postmenopausal women with …

F Khanizadeh, A Rahmani, K Asadollahi… - … of endocrinology and …, 2018 - SciELO Brasil
Objective: This study evaluated the effects of combination therapy of curcumin and
alendronate on BMD and bone turnover markers in postmenopausal women with …

[HTML][HTML] Decoding the synergistic potential of herbal medicine and dietary supplements for treating postmenopausal osteoporosis

J Dou, X Hu, J Liu, J Liu, C Zhang, Y Zhang… - Experimental …, 2025 - Elsevier
Purpose The exploration of the combined effects of FLL and quinoa presents an intriguing
opportunity to enhance the efficacy of osteoporosis treatment. Methods This study aimed to …