Nuclear RNase MRP is Required for Correct Processing of pre-5.8S rRNA in Saccharomyces cerevisiae
ME Schmitt, DA Clayton - Molecular and cellular biology, 1993 - Taylor & Francis
RNase MRP is a site-specific ribonucleoprotein endoribonuclease that cleaves RNA from
the mitochondrial origin of replication in a manner consistent with a role in priming leading …
the mitochondrial origin of replication in a manner consistent with a role in priming leading …
Yeast site-specific ribonucleoprotein endoribonuclease MRP contains an RNA component homologous to mammalian RNase MRP RNA and essential for cell viability …
ME Schmitt, DA Clayton - Genes & development, 1992 - genesdev.cshlp.org
RNase MRP is a site-specific ribonucleoprotein endoribonuclease that cleaves RNA
sequence complementary to mammalian mitochondrial origins of replication in a manner …
sequence complementary to mammalian mitochondrial origins of replication in a manner …
Saccharomyces cerevisiae Contains an RNase MRP That Cleaves at a Conserved Mitochondrial RNA Sequence Implicated in Replication Priming
LL Stohl, DA Clayton - Molecular and cellular biology, 1992 - Taylor & Francis
Yeast mitochondrial DNA contains multiple promoters that sponsor different levels of
transcription. Several promoters are individually located immediately adjacent to presumed …
transcription. Several promoters are individually located immediately adjacent to presumed …
Nuclear RNase MRP processes RNA at multiple discrete sites: interaction with an upstream G box is required for subsequent downstream cleavages.
R Karwan, JL Bennett, DA Clayton - Genes & development, 1991 - genesdev.cshlp.org
RNase MRP is a site-specific endoribonuclease that processes primer RNA from the leading-
strand origin of mammalian mitochondrial DNA replication. It is present in active form as …
strand origin of mammalian mitochondrial DNA replication. It is present in active form as …
A nuclear function for RNase MRP.
DA Clayton - Proceedings of the National Academy of …, 1994 - National Acad Sciences
The site-specific endoribonuclease RNase MRP was first identified 7 years ago as an RNA-
processing activity in mammalian cells (1, 2). In the original description of this …
processing activity in mammalian cells (1, 2). In the original description of this …
Characterization and purification of Saccharomyces cerevisiae RNase MRP reveals a new unique protein component
K Salinas, S Wierzbicki, L Zhou, ME Schmitt - Journal of Biological …, 2005 - ASBMB
In the yeast Saccharomyces cerevisiae, RNase mitochondrial RNA processing (MRP) is an
essential endoribonuclease that consists of one RNA component and at least nine protein …
essential endoribonuclease that consists of one RNA component and at least nine protein …
Characterization of a unique protein component of yeast RNase MRP: an RNA-binding protein with a zinc-cluster domain.
ME Schmitt, DA Clayton - Genes & Development, 1994 - genesdev.cshlp.org
RNase MRP is a ribonucleoprotein endoribonuclease that has been shown to cleave
mitochondrial primer RNA sequences from a variety of sources. Most of the RNase MRP …
mitochondrial primer RNA sequences from a variety of sources. Most of the RNase MRP …
The RNA of RNase MRP is required for normal processing of ribosomal RNA.
S Chu, RH Archer, JM Zengel… - Proceedings of the …, 1994 - National Acad Sciences
We have isolated clones which complement the temperature sensitivity and abnormal rRNA
processing pattern of the rrp2-2 mutant of Saccharomyces cerevisiae we previously …
processing pattern of the rrp2-2 mutant of Saccharomyces cerevisiae we previously …
Characterization of human MRP/Th RNA and its nuclear gene: full length MRP/Th RNA is an active endoribonuclease when assembled as an RNP
JN Topper, DA Clayton - Nucleic acids research, 1990 - academic.oup.com
Vertebrate cells contain a site-specific endoribonuclease (RNase MRP) that cleaves
mitochondrial RNA transcribed from the origin of leading-strand mitochondrial DNA …
mitochondrial RNA transcribed from the origin of leading-strand mitochondrial DNA …
Mouse RNAase MRP RNA is encoded by a nuclear gene and contains a decamer sequence complementary to a conserved region of mitochondrial RNA substrate
DD Chang, DA Clayton - Cell, 1989 - cell.com
Using complementary oligonucleotide probes, we have isolated the nuclear gene for the
RNA moiety of RNAase MRP; it is present as a single copy and encodes an uncapped …
RNA moiety of RNAase MRP; it is present as a single copy and encodes an uncapped …