Primary Sjögren's syndrome is a systemic autoimmune disease characterized by
progressive exocrine gland destruction, resulting clinically in eyes and mouth dryness. To …

The management of patients with primary Sjogren syndrome (pSS) has long suffered from
the lack of effective treatments. Progress made in the understanding of pSS pathogenesis …

Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterized by
dryness and systemic involvement in more than a third of the patients. Patient management …

Sjögren's syndrome (SS) is a systemic autoimmune disease that affects the exocrine glands,
mainly the salivary and lachrymal glands, with consequent persistent dryness of the mouth …

Biological abnormalities associated with B lymphocytes are a hallmark of patients with
primary Sjögren's syndrome. Those patients present abnormal distribution of B lymphocytes …

Conventionnal therapy (moisturizers, pilocarpine, Cevimeline, local Cyclosporine, and
hydroxychloroquine) remains the basis for the treatment of primary Sjögren's syndrome …

Importance of the field: Sjögren's syndrome (SS) is an autoimmune epithelitis. This
exocrinopathy is frequently associated with extraglandular complications, and the patients …

Introduction Sjögren's syndrome (SS) is an immune-mediated inflammatory condition
characterized by sicca syndrome, musculoskeletal pain, and fatigue. Extra-glandular …

Primary Sjögren's syndrome (pSS) is a systemic multiorgan autoimmune disease that runs a
chronic progressive course. The recently developed treat-to-target paradigm involves …

Despite the well-established role of B cells in the pathogenesis of primary Sjögren's
syndrome (pSS), the beneficial role of B-cell depletion therapy with rituximab remains …