The interphase nucleus and nuclear envelope can acquire a myriad of shapes in normal or
pathological cell states. There exist a wide variety of indentations and invaginations, of …

Abstract “Interphase epichromatin” describes the surface of chromatin located adjacent to
the interphase nuclear envelope. It was discovered in 2011 using a bivalent anti …

Alterations in nuclear shape are present in human diseases and ageing. A compromised
nuclear lamina is molecularly interlinked to altered chromatin functions and genomic …

Nuclear envelope-limited chromatin sheets (ELCS) form during excessive interphase
nuclear envelope growth in a variety of cells. ELCS appear as extended sheets within the …

Nuclear envelope-limited chromatin sheets (ELCS) are enigmatic membranous structures of
uncertain function. This study describes the induction of ELCS in p53 mutated Burkitt's …

The nucleus is a highly structured organelle with many chromatin and protein compartments
that partition the genome into regulatory domains. One such a compartment within the …

The nuclear envelope separates nuclear and cytoplasmic activities, and it controls all
macromolecular exchange between nucleus and cytoplasm. III addition, it helps to …

In the past 15 years our perception of nuclear envelope function has evolved perhaps nearly
as much as the nuclear envelope itself evolved in the last 3 billion years. Historically viewed …

The past decades have provided remarkable insights into how the eukaryotic cell nucleus
and the genome within it are organized. The combined use of imaging, biochemistry and …

Heterochromatin was first defined by Emil Heitz in 1928 by light microscopy. In the 1950s
electron microscopy studies revealed that heterochromatin preferentially localizes to the …