Homocysteine and holotranscobalamin and the risk of Alzheimer disease: a longitudinal study

B Hooshmand, A Solomon, I Kåreholt, J Leiviskä… - Neurology, 2010 - AAN Enterprises
Objective: To examine the relation between serum levels of homocysteine (tHcy) and
holotranscobalamin (holoTC), the active fraction of vitamin B12, and risk of incident …

Homocysteine and holo‐transcobalamin and the risk of dementia and Alzheimers disease: a prospective study

M Kivipelto, S Annerbo, J Hultdin… - European Journal of …, 2009 - Wiley Online Library
Background: Elevated total homocysteine (tHcy) levels may be caused by vitamin B12
deficiency and are linked to Alzheimers disease (AD) in some studies, although the …

Associations between homocysteine, folic acid, vitamin B12 and Alzheimer's disease: insights from meta-analyses

L Shen, HF Ji - Journal of Alzheimer's Disease, 2015 - content.iospress.com
The associations between homocysteine (Hcy), folic acid, and vitamin B12 and Alzheimer's
disease (AD) have gained much interest, while remaining controversial. We aim to perform …

Associations between Alzheimer's disease and blood homocysteine, vitamin B12, and folate: a case-control study

H Chen, S Liu, L Ji, T Wu, F Ma, Y Ji… - Current Alzheimer …, 2015 - ingentaconnect.com
Background: There is a growing focus on nutritional therapy for Alzheimer's disease (AD),
and controversy exists regarding the association between AD and homocysteine (Hcy) …

Serum Homocysteine, Vitamin B 12, Folate, and Their Association with Mild Cognitive Impairment and Subtypes of Dementia

Y Song, M Quan, T Li, J Jia - Journal of Alzheimer's Disease, 2022 - content.iospress.com
Background: Although elevated levels of homocysteine (Hcy) are associated with cognitive
impairment and dementia, the relevance of Hcy, vitamin B12, and folate levels to subtypes of …

Plasma homocysteine, vitamin B12 and folate in Alzheimer's patients and healthy Arabs in Israel

EH Mizrahi, A Bowirrat, DW Jacobsen… - Journal of the …, 2004 - Elsevier
High plasma homocysteine (tHcy) is a risk factor for cardiovascular disease and stroke and
Alzheimer's disease (AD). An inverse relationship has been reported between tHcy and …

Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal study

B Hooshmand, A Solomon, I Kåreholt… - Journal of internal …, 2012 - Wiley Online Library
Hooshmand B, Solomon A, Kåreholt I, Rusanen M, Hänninen T, Leiviskä J, Winblad B,
Laatikainen T, Soininen H & Kivipelto M (Aging Research Center, Karolinska Institutet …

Plasma Homocysteine and Serum Folate and Vitamin B12 Levels in Mild Cognitive Impairment and Alzheimer's Disease: A Case-Control Study

F Ma, T Wu, J Zhao, L Ji, A Song, M Zhang, G Huang - Nutrients, 2017 - mdpi.com
Homocysteine (Hcy) is a risk factor for brain atrophy, cognitive impairment, and dementia.
Vitamin B12 and folate are cofactors necessary for the methylation of Hcy. However, there is …

Serum homocysteine and dementia: meta-analysis of eight cohort studies including 8669 participants

DS Wald, A Kasturiratne, M Simmonds - Alzheimer's & Dementia, 2011 - Elsevier
BACKGROUND: Prospective cohort studies have not been consistent in showing an
association between serum homocysteine and dementia. OBJECTIVE: To conduct a meta …

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

S Seshadri, A Beiser, J Selhub… - New England journal …, 2002 - Mass Medical Soc
Background In cross-sectional studies, elevated plasma homocysteine levels have been
associated with poor cognition and dementia. Studies of newly diagnosed dementia are …