Use of biologics in Sjögren's syndrome

G Nocturne, D Cornec, R Seror… - Rheumatic Disease …, 2016 - rheumatic.theclinics.com
The management of patients with primary Sjogren syndrome (pSS) has long suffered from
the lack of effective treatments. Progress made in the understanding of pSS pathogenesis …

The future of B cell-targeted therapies in Sjögren's syndrome

D Cornec, A Saraux, V Devauchelle-Pensec… - …, 2013 - Taylor & Francis
Primary Sjögren's syndrome is a systemic autoimmune disease characterized by
progressive exocrine gland destruction, resulting clinically in eyes and mouth dryness. To …

Emerging biological therapies in primary Sjögren's syndrome

M Ramos-Casals, P Brito-Zerón - Rheumatology, 2007 - academic.oup.com
Sjögren's syndrome (SS) is a systemic autoimmune disease that mainly affects the exocrine
glands and usually presents as persistent dryness of the mouth and eyes. SS primarily …

Treating Sjögren's syndrome: insights for the clinician

C Vitali, G Palombi, P Cataleta - Therapeutic Advances in …, 2010 - journals.sagepub.com
Sjögren's syndrome (SS) is a systemic autoimmune disease that affects the exocrine glands,
mainly the salivary and lachrymal glands, with consequent persistent dryness of the mouth …

The pipeline of targeted therapies under clinical development for primary Sjögren's syndrome: a systematic review of trials

R Felten, F Scher, J Sibilia, JE Gottenberg… - Autoimmunity Reviews, 2019 - Elsevier
To date, no immunomodulatory drug has proved efficacious in primary Sjögren's syndrome
(pSS). In pSS, difficulties in drug efficacy assessment is related to the large spectrum of …

New biological therapies in Sjögren's syndrome

G Nocturne, D Cornec, R Seror, X Mariette - Best Practice & Research …, 2015 - Elsevier
Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterized by
dryness and systemic involvement in more than a third of the patients. Patient management …

Biologics in Sjögren's syndrome

C Skarlis, N Marketos, CP Mavragani - Pharmacological Research, 2019 - Elsevier
The use of biologic disease modifying antirheumatic drugs (bDMARDs) in systemic
autoimmune diseases such as rheumatoid arthritis and at a lesser extent in lupus, has been …

Emerging biotherapies for Sjögren's syndrome

GJ Tobón, A Saraux, JO Pers… - Expert Opinion on …, 2010 - Taylor & Francis
Importance of the field: Sjögren's syndrome (SS) is an autoimmune epithelitis. This
exocrinopathy is frequently associated with extraglandular complications, and the patients …

Biologic treatment in Sjögren's syndrome

PR Sada, D Isenberg, C Ciurtin - Rheumatology, 2015 - academic.oup.com
SS is a chronic systemic autoimmune disease characterized by decreased exocrine gland
function. A variety of other disease manifestations may also be present, including general …

New developments in Sjogren's syndrome

N Thalayasingam, K Baldwin, C Judd, WF Ng - Rheumatology, 2021 - academic.oup.com
SS is a chronic, autoimmune condition characterized by lymphocytic infiltration of the
exocrine glands and B-cell dysfunction. Current treatment strategies are largely empirical …