Protective effect of selenium supplementation on the genotoxicity of di (2-ethylhexyl) phthalate and mono (2-ethylhexyl) phthalate treatment in LNCaP cells

P Erkekoğlu, W Rachidi, V De Rosa, B Giray… - Free Radical Biology …, 2010 - Elsevier
Selenium is an essential cofactor in the key enzymes involved in cellular antioxidant
defense. It plays a critical role in testis and reproduction and regulates DNA damage within …

Evaluation of cytotoxicity and oxidative DNA damaging effects of di (2-ethylhexyl)-phthalate (DEHP) and mono (2-ethylhexyl)-phthalate (MEHP) on MA-10 Leydig cells …

P Erkekoglu, W Rachidi, OG Yuzugullu, B Giray… - Toxicology and applied …, 2010 - Elsevier
Di (2-ethylhexyl)-phthalate (DEHP) is the most abundantly used phthalate derivative,
inevitable environmental exposure of which is suspected to contribute to the increasing …

Induction of ROS, p53, p21 in DEHP-and MEHP-exposed LNCaP cells-protection by selenium compounds

P Erkekoğlu, W Rachidi, OG Yüzügüllü, B Giray… - Food and Chemical …, 2011 - Elsevier
This study was designed to investigate the hypothesis that the toxic effects of di (2-
ethylhexyl) phthalate (DEHP), the most abundantly used plasticizer and ubiquitous …

Effects of di (2‐ethylhexyl) phthalate on testicular oxidant/antioxidant status in selenium‐deficient and selenium‐supplemented rats

P Erkekoglu, B Giray, W Rachidi… - Environmental …, 2014 - Wiley Online Library
Di (ethylhexyl) phthalate (DEHP), the most widely used plasticizer, was investigated to
determine whether an oxidative stress process was one of the underlying mechanisms for its …

The effects of di (2-ethylhexyl) phthalate and/or selenium on trace element levels in different organs of rats

P Erkekoglu, J Arnaud, W Rachidi… - Journal of Trace …, 2015 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP), a widely used plasticizer for synthetic polymers,
is known to have endocrine disruptive potential, reproductive toxicity, and induces hepatic …

The effects of di (2-ethylhexyl) phthalate exposure and selenium nutrition on sertoli cell vimentin structure and germ-cell apoptosis in rat testis

P Erkekoglu, ND Zeybek, B Giray, E Asan… - Archives of …, 2012 - Springer
This study aimed to investigate the effects of di (2-ethylhexyl) phthalate (DEHP) on Sertoli-
cell vimentin filaments and germ-cell apoptosis in testes of pubertal rats at different selenium …

Reproductive toxicity of di (2-ethylhexyl) phthalate in selenium-supplemented and selenium-deficient rats

P Erkekoglu, ND Zeybek, B Giray, E Asan… - Drug and Chemical …, 2011 - Taylor & Francis
Phthalates are abundantly produced plasticizers, and di (ethylhexyl) phthalate (DEHP) is the
most widely used derivative in various consumer products and medical devices. Animal …

Oxidative DNA damage induced by di-(2-ethylhexyl) phthalate in HEK-293 cell line

X Wang, L Jiang, L Ge, M Chen, G Yang, F Ji… - Environmental …, 2015 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is commonly employed as a plasticizer. We
have found that exposure of human embryonic kidney cell line 293 (HEK-293) to DEHP …

Thyroidal effects of di-(2-ethylhexyl) phthalate in rats of different selenium status

P Erkekoglu, B Kocer-Gumusel… - Journal of …, 2012 - dl.begellhouse.com
This study was designed to investigate the effects of di-(2-ethylhexyl) phthalate (DEHP) on
thyroid hormone levels and oxidant/antioxidant parameters in the rat and to evaluate the …

[HTML][HTML] Nano-sized selenium attenuates the developmental testicular toxicity induced by di-n-butyl phthalate in pre-pubertal male rats

MM Rashad, MK Galal, KS Abou-El-Sherbini… - Biomedicine & …, 2018 - Elsevier
The current study was conducted to test the possible ameliorative role of selenium
nanoparticles (Se-NPs) against oxidative damage of Leyding cells induced by di-n-butyl …