Modifications of nano-titania surface for in vitro evaluations of hemolysis, cytotoxicity, and nonspecific protein binding

A Datta, S Dasgupta, S Mukherjee - Journal of Nanoparticle Research, 2017 - Springer
In the past decade, a variety of drug carriers based on mesoporous silica nanoparticles has
been extensively reported. However, their biocompatibility still remains debatable, which …

Impact of mesoporous silica nanoparticle surface functionality on hemolytic activity, thrombogenicity and non-specific protein adsorption

A Yildirim, E Ozgur, M Bayindir - Journal of Materials Chemistry B, 2013 - pubs.rsc.org
Although numerous mesoporous silica nanoparticle (MSN) drug carriers and theranostic
agents with various surface functionalities have been designed in the last decade, their …

Moving into advanced nanomaterials. Toxicity of rutile TiO2 nanoparticles immobilized in nanokaolin nanocomposites on HepG2 cell line

MJ Bessa, C Costa, J Reinosa, C Pereira… - Toxicology and applied …, 2017 - Elsevier
Immobilization of nanoparticles on inorganic supports has been recently developed,
resulting in the creation of nanocomposites. Concerning titanium dioxide nanoparticles (TiO …

Different toxicity of anatase and rutile TiO2 nanoparticles on macrophages: involvement of difference in affinity to proteins and phospholipids

Q Yu, H Wang, Q Peng, Y Li, Z Liu, M Li - Journal of hazardous materials, 2017 - Elsevier
TiO 2 nanoparticles (NPs) are well-known nanomaterials (NMs), widely used in cosmetics,
solar cells, photo-catalysts and additives. Anatase and rutile are the two main crystalline …

Preparation and evaluation of the cytotoxic nature of TiO2 nanoparticles by direct contact method

M Chellappa, U Anjaneyulu… - International journal …, 2015 - Taylor & Francis
The purpose of this study is to prepare and evaluate the effect of synthesized titanium
dioxide (TiO2) nanoparticles for their biocompatibility on physiological body fluids and the …

Excess titanium dioxide nanoparticles on the cell surface induce cytotoxicity by hindering ion exchange and disrupting exocytosis processes

Y Wang, C Yao, C Li, L Ding, J Liu, P Dong, H Fang… - Nanoscale, 2015 - pubs.rsc.org
To date, considerable effort has been devoted to determine the potential toxicity of
nanoparticles to cells and organisms. However, determining the mechanism of cytotoxicity …

The effect of blood protein adsorption on cellular uptake of anatase TiO2 nanoparticles

ZE Allouni, NR Gjerdet, MR Cimpan… - International Journal of …, 2015 - Taylor & Francis
Protein adsorption onto nanoparticles (NPs) in biological fluids has emerged as an
important factor when testing biological responses to NPs, as this may influence both uptake …

Surface functionalized mesoporous silica nanoparticles with natural proteins for reduced immunotoxicity

Z Luo, Y Hu, R Xin, B Zhang, J Li, X Ding… - … Research Part A, 2014 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs) present themselves as one of the most promising
nano‐carriers for drug delivery. To reduce their immunotoxicities, in this study, natural …

The effect of the shape of mesoporous silica nanoparticles on cellular uptake and cell function

X Huang, X Teng, D Chen, F Tang, J He - Biomaterials, 2010 - Elsevier
The interaction between nanoparticles (NPs) and cells has been studied extensively, but the
effect of particle shape on cell behavior has received little attention. Herein three different …

Impact of the Physicochemical Features of TiO2 Nanoparticles on Their In Vitro Toxicity

O Kose, M Tomatis, L Leclerc… - Chemical research in …, 2020 - ACS Publications
The concern about titanium dioxide nanoparticles (TiO2-NPs) toxicity and their possible
harmful effects on human health has increased. Their biological impact is related to some …