Primary Sjögren syndrome (pSS) is a prototypical autoimmune disease. The involvement of
B cells in the pathogenesis of pSS has long been suspected on the basis of clinical …

Primary Sjögren's syndrome (pSS) is a chronic autoimmune systemic disease, characterized
by a lymphoplasmocytic infiltration and a progressive destruction of salivary and lachrymal …

Advances in the understanding of pSS pathogenesis have paved the way for clinical trials
with novel biologic agents targeting immune pathways regulating T/B-cell interactions and …

Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease characterized by
lymphocytic infiltration and tissue destruction of exocrine glands such as salivary glands …

Sjögren's syndrome (SS) is an autoimmune epithelitis hallmarked by a destruction of
epithelial cells, the subsequent lymphocytic infiltration of exocrine glands and their ensuing …

A histologic hallmark of primary SS (pSS) is lymphocytic infiltration of the salivary and
lacrimal glands, in particular by CD4+ T and B cells. In the early stages of the disease …

Progress made during the last few years on the pathogenesis of pSS has been mirrored by
clinical trials directed at inhibiting cytokines, B, or T cell responses. Future efforts should …

SS is an autoimmune condition characterized by exocrine gland destruction, autoantibody
production, immune complex deposition and systemic complications associated with …

Primary Sjögren's syndrome (pSS) is characterized by mononuclear inflammatory infiltrates
and IgG plasma cells in salivary and lacrimal glands which lead to irreversible destruction of …

Primary Sjögren's syndrome (SS) is a common chronic autoimmune disease characterized
by lymphocytic infiltration of exocrine glands, mainly salivary and lacrimal, resulting in oral …