Mesenchymal stem cells (MSCs) exert their therapeutic capability through a variety of
bioactive substances, including trophic factors, microRNAs, and extracellular vesicles (EVs) …

A major clinical hurdle to translate MSC-derived extracellular vesicles (EVs) is the lack of a
method to scale-up the production of EVs with customized therapeutic properties. In this …

Stroke is the leading cause of physical disability among adults. Stem cells such as
mesenchymal stem cells (MSCs) secrete a variety of bioactive substances, including trophic …

A stroke is a focal cerebral insult that frequently causes severe neurological deficit and
mortality. Recent studies have demonstrated that multipotent mesenchymal stromal cells …

Obtained from the right cell-type, mesenchymal stromal cell (MSC)-derived small
extracellular vesicles (sEVs) promote stroke recovery. Within this process, microvascular …

Cell-based therapy, eg, multipotent mesenchymal stromal cell (MSC) treatment, shows
promise for the treatment of various diseases. The strong paracrine capacity of these cells …

Stem cells such as mesenchymal stem cells (MSCs) enhance neurological recovery in
preclinical stroke models by secreting extracellular vesicles (EVs). Since previous reports …

Stem cell-based treatments have been suggested as promising candidates for stroke.
Recently, mesenchymal stem cells (MSCs) have been reported as potential therapeutics for …

Transplantation of mesenchymal stem cells (MSCs) was reported to improve functional
outcomes in a rat model of ischemic stroke, and subsequent studies suggest that MSC …

Although the initial concepts of stem cell therapy aimed at replacing lost tissue, more recent
evidence has suggested that stem and progenitor cells alike promote postischemic …