Abstract Hydrogen peroxide (H 2 O 2), an oxidizing agent, has been widely used as a
disinfectant. Recently, because of its reactive properties, H 2 O 2 has also been used as a …

Objectives To evaluate the effect of the oxidative stress on human dental pulp cells (HDPCs)
promoted by toxic concentrations of hydrogen peroxide (H 2 O 2) on its odontoblastic …

Although the induction of heme oxygenase–1 (HO-1) by hydrogen peroxide (H2O2) has
been reported, the HO-1 and odontoblastic differentiation-inducing effects against …

Numerous studies have shown that hydrogen peroxide (H2O2) inhibits proliferation and
osteoblastic differentiation in bone‐like cells. Human periodontal ligament fibroblasts (PLF) …

Objective This study provides an in vivo evaluation of the inflammatory response, levels of
cell proliferation and apoptosis, and the presence of necrosis after dental bleaching with two …

The aim of this study was to evaluate the trans-enamel and trans-dentinal effects of a 35%
hydrogen peroxide (H2O2) bleaching gel on odontoblast-like cells. Enamel/dentin discs …

Oxidative stress regulates cellular functions in multiple pathological conditions, including
bone formation by osteoblastic cells. However, little is known about the cellular mechanisms …

The molecular mechanisms underlying the pathophysiology of bone destruction still remain
poorly understood. We have found that hydrogen peroxide (H 2 O 2), a reactive oxygen …

Reactive oxygen species such as superoxide and hydrogen peroxide have been implicated
as regulatory factors in the control of osteoclastic bone resorption. While superoxide radicals …

Objective To evaluate the effect of a 17.5% H 2 O 2 gel on the odontoblastic differentiation
capability of human dental pulp cells (HDPCs). Design The bleaching gel was applied for …