The nuclear envelope as a chromatin organizer

N Zuleger, MI Robson, EC Schirmer - Nucleus, 2011 - Taylor & Francis
In the past 15 years our perception of nuclear envelope function has evolved perhaps nearly
as much as the nuclear envelope itself evolved in the last 3 billion years. Historically viewed …

The nuclear envelope

EA Nigg - Current opinion in cell biology, 1989 - Elsevier
The nuclear envelope separates nuclear and cytoplasmic activities, and it controls all
macromolecular exchange between nucleus and cytoplasm. III addition, it helps to …

Nuclear envelope: connecting structural genome organization to regulation of gene expression

I Stancheva, EC Schirmer - Cancer Biology and the Nuclear Envelope …, 2014 - Springer
For many years, the nuclear envelope was viewed as a passive barrier that separates the
genetic material in the nucleus from the cytoplasm of the cell and permits regulated …

The biology of the nuclear envelope and its implications in cancer biology

M Alvarado-Kristensson, CA Rosselló - International journal of molecular …, 2019 - mdpi.com
The formation of the nuclear envelope and the subsequent compartmentalization of the
genome is a defining feature of eukaryotes. Traditionally, the nuclear envelope was purely …

The nuclear envelope

MW Hetzer - Cold Spring Harbor perspectives in biology, 2010 - cshperspectives.cshlp.org
The nuclear envelope (NE) is a highly regulated membrane barrier that separates the
nucleus from the cytoplasm in eukaryotic cells. It contains a large number of different …

Sizing up the nucleus: nuclear shape, size and nuclear-envelope assembly

M Webster, KL Witkin, O Cohen-Fix - Journal of cell science, 2009 - journals.biologists.com
The nucleus is one of the most prominent cellular organelles, yet surprisingly little is known
about how it is formed, what determines its shape and what defines its size. As the nuclear …

The nuclear envelope: form and reformation

AJ Prunuske, KS Ullman - Current opinion in cell biology, 2006 - Elsevier
The membrane system that encloses genomic DNA is referred to as the nuclear envelope.
However, with emerging roles in signaling and gene expression, these membranes clearly …

The functions of the nuclear envelope in mediating the molecular crosstalk between the nucleus and the cytoplasm

T Shimi, V Butin-Israeli, RD Goldman - Current opinion in cell biology, 2012 - Elsevier
Recent studies of the nuclear envelope (NE) have emphasized its role in linking the nuclear
and cytoplasmic compartments of mammalian cells. The inner face of the NE is bound to …

Blurring the boundary: the nuclear envelope extends its reach

CL Stewart, KJ Roux, B Burke - Science, 2007 - science.org
The past decade has seen a complete rethinking of the traditional view of the nuclear
envelope as simply a passive enclosure for the chromosomes. The convergence of several …

Remodelling the walls of the nucleus

B Burke, J Ellenberg - Nature reviews molecular cell biology, 2002 - nature.com
The nuclear envelope (NE) acts as a selective barrier around the genome and as a scaffold
to organize DNA in the nucleus. During cell division, the NE is broken down and …