Blood and CSF homocysteine levels in Alzheimer's disease: A meta-analysis and meta-regression of case–control studies

L Zhang, X Xie, Y Sun, F Zhou - Neuropsychiatric Disease and …, 2022 - Taylor & Francis
Objective Hyperhomocysteinemia (HHcy), as an important risk factor for Alzheimer's disease
(AD), would aggravate cognitive dysfunction. This study aimed to investigate whether and to …

Homocysteine and folic acid: risk factors for Alzheimer's disease—an updated Meta-analysis

Q Wang, J Zhao, H Chang, X Liu, R Zhu - Frontiers in aging …, 2021 - frontiersin.org
Background: Recent studies have reported that homocysteine (Hcy) may play a vital role in
the pathogenesis of vascular dementia (VaD) and Alzheimer's disease (AD). Our study …

Elevated blood homocysteine and risk of Alzheimer's Dementia: an updated systematic review and meta-analysis based on prospective studies

M Zuin, C Cervellati, G Brombo, A Trentini… - The Journal of …, 2021 - Springer
Objective To investigate whether high serum homocysteine (Hcy) levels is associated with
the risk of developing Alzheimer's disease (AD) by performing a meta-analysis based on …

Associations between homocysteine, folic acid, vitamin B12 and Alzheimer's disease: insights from meta-analyses

L Shen, HF Ji - Journal of Alzheimer's Disease, 2015 - content.iospress.com
The associations between homocysteine (Hcy), folic acid, and vitamin B12 and Alzheimer's
disease (AD) have gained much interest, while remaining controversial. We aim to perform …

Hyperhomocysteinemia and Alzheimer's disease: A systematic review

F Van Dam, WA Van Gool - Archives of gerontology and geriatrics, 2009 - Elsevier
Hyperhomocysteinemia (HHcy) is supposed to be one of the modifiable risk factors that, if
treated, may delay the onset of Alzheimer's disease (AD). The relation between serum …

Association between homocysteine levels and cognitive profile in Alzheimer's Disease

S Luzzi, G Papiri, G Viticchi, S Baldinelli, C Fiori… - Journal of Clinical …, 2021 - Elsevier
Background Growing evidence suggests that hyperhomocysteinemia (HHcy) constitutes a
risk factor for Alzheimer's Disease (AD). The impact of HHcy on cognitive functions has …

Serum homocysteine and dementia: meta-analysis of eight cohort studies including 8669 participants

DS Wald, A Kasturiratne, M Simmonds - Alzheimer's & Dementia, 2011 - Elsevier
BACKGROUND: Prospective cohort studies have not been consistent in showing an
association between serum homocysteine and dementia. OBJECTIVE: To conduct a meta …

Plasma Homocysteine and Serum Folate and Vitamin B12 Levels in Mild Cognitive Impairment and Alzheimer's Disease: A Case-Control Study

F Ma, T Wu, J Zhao, L Ji, A Song, M Zhang, G Huang - Nutrients, 2017 - mdpi.com
Homocysteine (Hcy) is a risk factor for brain atrophy, cognitive impairment, and dementia.
Vitamin B12 and folate are cofactors necessary for the methylation of Hcy. However, there is …

Homocysteine concentrations in the cognitive progression of Alzheimer's disease

N Farina, F Jernerén, C Turner, K Hart, N Tabet - Experimental Gerontology, 2017 - Elsevier
Abstract Objectives Hyperhomocysteinemia in Alzheimer's disease (AD) is widely reported
and appears to worsen as the disease progresses. While active dietary intervention with …

Associations between Alzheimer's disease and blood homocysteine, vitamin B12, and folate: a case-control study

H Chen, S Liu, L Ji, T Wu, F Ma, Y Ji… - Current Alzheimer …, 2015 - ingentaconnect.com
Background: There is a growing focus on nutritional therapy for Alzheimer's disease (AD),
and controversy exists regarding the association between AD and homocysteine (Hcy) …