Hematological and biochemical reference values in sickle cell disease (SCD) are crucial for
patient management and the evaluation of interventions. This study was conducted at …

Background: Sickle cell disease (SCD) remains a major health burden in Sub-Saharan
Africa and the management requires regular monitoring of the patients. The monitoring …

Background: Sickle cell anemia (SCA) is the most common and severest form of sickle cell
disease. It affects about 3% of the Nigerian population with a high mortality in children …

Abstract Background: Sub-Saharan Africa has the largest burden and worst outcome of
sickle cell disease (SCD). This gloomy outlook has been attributed to the lack of use of …

Background: Sickle cell disease is a genetic abnormality involving the haemoglobin
synthesis. Although it is a primary red cell disorder, white blood cells (WBC) and platelets …

The heterogeneity in clinical presentations in sickle cell disease (SCD) alters between crisis
and steady state phases. Considering the pathophysiology, it is crucial to establish a …

Background Sickle cell disease (SCD) accounts for 5% of mortality in African children aged<
5 years. Improving the care management and quality of life of patients with SCD requires a …

Background In the Democratic Republic of Congo, the incidence of sickle cell anemia (SCA)
is estimated around 40 000 neonates per year. However, it is notoriously difficult to perform …

Background: Sickle cell anaemia (SCA) is a major cause of morbidity and mortality in Africa
where there is no readily available effective treatment. This study was designed to determine …

Introduction: Sickle cell disease (SCD) has a wide range of clinical presentation. We
evaluated hematological parameters, which are widely evaluable and assessable, as …