Efficacy and safety of apremilast monotherapy in moderate‐to‐severe plaque psoriasis: A systematic review and meta‐analysis

YE Aljefri, AA Ghaddaf, TA Alkhunani… - Dermatologic …, 2022 - Wiley Online Library
Psoriasis is a chronic, inflammatory, immune‐mediated disease of the skin and joints.
Plaque psoriasis is the most common clinical phenotype of psoriasis. Apremilast is an oral …

Efficacy and safety of apremilast monotherapy for moderate to severe psoriasis: retrospective study

A Ighani, JR Georgakopoulos, LL Zhou… - Journal of …, 2018 - journals.sagepub.com
Background: Apremilast is a new oral drug for the treatment of moderate to severe plaque
psoriasis that reduces inflammation by inhibiting phosphodiesterase 4. Its efficacy and safety …

Apremilast for the management of moderate to severe plaque psoriasis

R Vangipuram, A Alikhan - Expert review of clinical pharmacology, 2017 - Taylor & Francis
Introduction: Psoriasis is a chronic inflammatory skin disease characterized by erythematous
plaques on extensor surfaces, scalp, and back. Current therapies for psoriasis are limited by …

An update on the safety of apremilast for the treatment of plaque psoriasis

E Shavit, NH Shear - Expert Opinion on Drug Safety, 2020 - Taylor & Francis
Introduction: Apremilast is an oral phosphodiesterase inhibitor, approved for moderate to
severe psoriasis in adults. Despite the advancement in dermatology, and the introduction of …

Long‐term efficacy and safety of apremilast in the treatment of plaques psoriasis: A real‐world, single‐center experience

G Radi, A Campanati, F Diotallevi… - Dermatologic …, 2021 - Wiley Online Library
Apremilast is a small molecule approved for the treatment of plaques psoriasis and adult
psoriatic arthritis. Pivotal studies have demonstrated short and long term efficacy and safety …

Long-term effectiveness and drug survival of apremilast in treating psoriasis: a real-world experience

J Distel, S Cazzaniga, SM Seyed Jafari, V Emelianov… - Dermatology, 2022 - karger.com
Background: Apremilast is an oral phosphodiesterase 4 (PDE4) inhibitor used for the
treatment of moderate to severe psoriasis. Long-term data on the effectiveness and drug …

Efficacy and safety of apremilast in the treatment of patients with mild-to-moderate psoriasis in Japan: results from PROMINENT, a phase 3b, open-label, single-arm …

Y Okubo, H Takahashi, R Hino, K Endo… - Dermatology and …, 2022 - Springer
Introduction Patients with mild-to-moderate plaque psoriasis often experience reduced
quality of life and increased disease burden due to itch or involvement of psoriasis in special …

[HTML][HTML] Treatment persistence and safety of Apremilast in psoriasis: experience with 30 patients in routine clinical practice

A Sahuquillo-Torralba, B de Unamuno Bustos… - Actas Dermo …, 2020 - Elsevier
Apremilast is a phosphodiesterase-4 inhibitor taken orally. Little information about its use in
routine clinical practice is available. We aimed to assess treatment safety and persistence …

The use of apremilast in psoriasis: an Indian perspective on real-world scenarios

M Rajagopalan, S Dogra, A Saraswat… - … : Targets and Therapy, 2021 - Taylor & Francis
Apremilast, an oral phosphodiesterase-4 inhibitor, is approved for use in the management of
psoriasis and psoriatic arthritis. Although its efficacy and safety have been well established …

[HTML][HTML] Improvement in scalp and nails with apremilast in patients with moderate plaque psoriasis naive to systemic and biologic therapy: 52-week results of the …

JM Jackson, A Alikhan, M Lebwohl… - 2018 - scholarlycommons.henryford.com
Background/Objective: Patients with moderate plaque psoriasis (ie, 5–10% psoriasis-
involved Body Surface Area [BSA]) often receive no treatment or are undertreated with …