[HTML][HTML] Microbiome-phage interactions in inflammatory bowel disease

S Federici, D Kviatcovsky, R Valdés-Mas… - Clinical microbiology and …, 2023 - Elsevier
Background Inflammatory bowel disease (IBD) constitutes a group of auto-inflammatory
disorders that impact the gastrointestinal tract and other systemic organs. The gut …

Phages and their role in gastrointestinal disease: focus on inflammatory bowel disease

M Maronek, R Link, L Ambro, R Gardlik - Cells, 2020 - mdpi.com
Inflammatory bowel diseases (IBDs) are a group of chronic autoinflammatory diseases
including Crohn's disease and ulcerative colitis. Although the molecular mechanisms …

[HTML][HTML] Pathological and therapeutic interactions between bacteriophages, microbes and the host in inflammatory bowel disease

J Babickova, R Gardlik - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
The intestinal microbiome is a dynamic system of interactions between the host and its
microbes. Under physiological conditions, a fine balance and mutually beneficial …

Bacteriophage-mediated manipulations of microbiota in gastrointestinal diseases

L El Haddad, JF Mendoza, C Jobin - Frontiers in Microbiology, 2022 - frontiersin.org
Although some gastrointestinal diseases could be managed using various antibiotics
regimen, this therapeutic approach lacks precision and damages the microbiota. Emerging …

Roles of gut bacteriophages in the pathogenesis and treatment of inflammatory bowel disease

L Qv, S Mao, Y Li, J Zhang, L Li - Frontiers in cellular and infection …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, are
chronic, relapsing intestinal inflammatory disorders. Although the molecular mechanisms …

The neglected gut microbiome: Fungi, Protozoa, and bacteriophages in inflammatory bowel disease

GL Guzzo, JM Andrews… - Inflammatory bowel …, 2022 - academic.oup.com
The gut microbiome has been implicated in the pathogenesis of inflammatory bowel disease
(IBD). Studies suggest that the IBD gut microbiome is less diverse than that of the unaffected …

Bacteriophages and their potential for treatment of gastrointestinal diseases

Y Duan, R Young, B Schnabl - Nature reviews Gastroenterology & …, 2022 - nature.com
Although bacteriophages have been overshadowed as therapeutic agents by antibiotics for
decades, the emergence of multidrug-resistant bacteria and a better understanding of the …

Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation

S Federici, S Kredo-Russo, R Valdés-Mas… - Cell, 2022 - cell.com
Human gut commensals are increasingly suggested to impact non-communicable diseases,
such as inflammatory bowel diseases (IBD), yet their targeted suppression remains a …

bacteriophages in gastroenterology—from biology to clinical applications

J Sabino, RP Hirten, JF Colombel - Alimentary pharmacology & …, 2020 - Wiley Online Library
Background The gut microbiota plays an important role in the pathogenesis of several
gastrointestinal diseases. Its composition and function are shaped by host‐microbiota and …

The human gut phage community and its implications for health and disease

P Manrique, M Dills, MJ Young - Viruses, 2017 - mdpi.com
In this review, we assess our current understanding of the role of bacteriophages infecting
the human gut bacterial community in health and disease. In general, bacteriophages …