In elderly women, after the menopause, which marks the end of reproductive life, estrogen
production and plasma levels represent only a small fraction of levels during reproductive …

Androgens in male senescence Page 1 CHAPTER 16 16 Contents 16.1 16.2 16.2.1 16.2.2
16.2.3 16.2.4 16.2.4.1 16.2.4.2 16.3 16.3.1 16.3.2 16.4 16.4.1 16.4.2 16.4.3 16.4.4 16.4.5 16.4.6 …

IN CONTRAST to the situation in women, where the menopause marks the end of the fertile
period, in men fertility persists into old age. Nevertheless old age in men is accompanied by …

Aging in men is accompanied by a gradual decline of all physiologcal functions, involving
the heart, lungs, kidneys, liver and brain as well as the endocrine system. The …

For centuries, the importance of the testes for the maintenance of male phenotype,
psychosexual behavior, and physical power has been recognized. Indeed, testicular extracts …

There is a statistical decline of testosterone levels in ageing men, most manifest in free
testosterone. While this fall is only moderate, ageing men show clinical signs of …

Most aging individuals die from atherosclerosis, cancer or dementia. In the oldest old also
loss of muscle strength resulting in frailty becomes the limiting factor for an individual's …

While the basics of testosterone production, effects and metabolism have been known for
decades, there has been a flow of novel insights in the genomics of testosterone action on a …

Aging in men is accompanied by a progressive, but individually variable decline of serum
testosterone production, more than 20% of healthy men over 60 yr of age presenting with …

T is now well accepted that serum testosterone (T) levels decline progressively with aging in
men (1–5). This decline is associated with alterations in body composition; diminished …