A method for measuring 5-L-oxoproline in urine, which involves isolation by short-column
chromatography, acid hydrolysis to glutamic acid and enzymic assay of glutamic acid, was …

l-5-oxoproline (l-5-OP) is an intermediate in glutathione synthesis, possibly limited by
cysteine availability. Urinary 5-OP excretion has been proposed as a measure of glycine …

We hypothesized that a limitation in the endogenous formation of glycine might constrain
catch-up growth during recovery from severe childhood malnutrition. The urinary excretion of …

Urinary 5-L-oxoproline was measured during normal pregnancies in Southampton, England
and Kingston, Jamaica. The CV of 5-L-oxoproline excretion in urine, determined over 7 d in …

1. The evidence is accumulating to suggest that glycine, the simplest amino acid, is
conditionally essential in man. Benzoic acid, by conjugation with glycine to form hippuric …

Abstract L-5-oxoproline (OP), an intermediate of the γ-glutamyl cycle of glutathione synthesis
and degradation, may serve as a probe for the state of glutathione kinetics. We explored the …

Arginine and proline derive from the metabolism of Δ1-pyrolline-5-carboxylate, a product of
intestinal glutamic acid metabolism. We studied the extent of glutamate, arginine, and …

This study examined plasma proline concentration flux, oxidation, and endogenous
biosynthesis in five healthy young men given three isocaloric, isonitrogenous diets for 1 wk …

Urinary 5-L-oxoproline was measured in term and preterm infants from shortly after birth until
6 weeks of postnatal age to determine their ability to synthesise glycine. In term infants the …

The effects of removing proline from the diet on plasma leucine and proline kinetics were
investigated. After a 1-wk control period, during which young adult men received a diet …