Cytokine profiles in the detection of severe lung involvement in hospitalized patients with COVID-19: The IL-8/IL-32 axis

L Bergantini, M d'Alessandro, P Cameli, A Otranto… - Cytokine, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is an infectious respiratory disorder caused
by a new coronavirus called SARS-CoV-2. The pathophysiology of severe COVID-19 is …

IL 33 correlates with COVID-19 severity, radiographic and clinical finding

SS Markovic, M Jovanovic, N Gajovic… - Frontiers in …, 2021 - frontiersin.org
Objective: The increased level of interleukin (IL)-33 is considered as a predictor of severe
coronavirus disease 2019 (COVID-19) infection, but its role at different stages of the disease …

Prognostic bioindicators in severe COVID-19 patients

L Bergantini, E Bargagli, M d'Alessandro, RM Refini… - Cytokine, 2021 - Elsevier
Background Severe acute respiratory syndrome caused by novel coronavirus 2 (SARS-CoV-
2) emerged in Wuhan (China) in December 2019. Here we evaluated a panel of biomarkers …

Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

H Han, Q Ma, C Li, R Liu, L Zhao, W Wang… - Emerging microbes & …, 2020 - Taylor & Francis
Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly
spread across many other countries. While the majority of patients were considered mild …

IL-33 depletion in COVID-19 lungs

R Gaurav, DR Anderson, SJ Radio, KL Bailey… - Chest, 2021 - journal.chestnet.org
IL-33 is an alarmin that plays an integral role in lung homeostasis through its actions in
wound repair, fibrosis, and remodeling processes. 1 Stored in the nucleus, IL-33 is released …

Deciphering the balance of IL-6/IL-10 cytokines in severe to critical COVID-19 patients

MB Azaiz, AB Jemaa, W Sellami, C Romdhani… - Immunobiology, 2022 - Elsevier
The severity of COVID-19 is largely determined by the inflammatory response, a “Cytokine
storm,” that involves both pro-and anti-inflammatory cytokines. In the current study we …

IL-33 and the cytokine storm in COVID-19: from a potential immunological relationship towards precision medicine

F Furci, G Murdaca, A Allegra, L Gammeri… - International Journal of …, 2022 - mdpi.com
Coronavirus SARS-CoV-2 has represented, and still represents, a real challenge from a
clinical, diagnostic and therapeutic point of view. During acute infection, the increased levels …

Interleukin-22 and interleukin-33 show up-regulated levels in the serum of patients with mild/moderate Coronavirus disease 2019

AY Majeed, NES Zulkafli, AH Ad'hiah - Beni-Suef University Journal of …, 2023 - Springer
Background This study analyzed serum concentrations of interleukin (IL)-22 and IL-33 (pro-
inflammatory and anti-inflammatory cytokines) in 90 patients with mild/moderate coronavirus …

Predicting roles of IL-27 and IL-32 in determining the severity and outcome of COVID-19

B Zamani, M Najafizadeh… - International …, 2022 - journals.sagepub.com
Objective Immune changes play fundamental roles in the pathogenesis and severity of
coronavirus disease 2019 (COVID-19). Previous studies have revealed alterations in …

Serum IL-23, IL-10, and TNF-α predict in-hospital mortality in COVID-19 patients

SW Smail, E Babaei, K Amin… - Frontiers in …, 2023 - frontiersin.org
Objective The hyperinflammatory response, caused by severe acute respiratory syndrome-2
(SARS-CoV-2), is the most common cause of death in patients with coronavirus disease …