Mycobactins are a family of membrane-associated siderophores required for Mycobacterium
tuberculosis to adapt to its intracellular habitat. These lipophilic siderophores have been …

To measure molecular changes underlying pathogen adaptation, we generated a
searchable dataset of more than 12,000 mass spectrometry events, corresponding to lipids …

Iron is essential for growth of Mycobacterium tuberculosis, the causative agent of
tuberculosis. To acquire iron from the host, M. tuberculosis uses the siderophores called …

Background: Many pathogenic bacteria secrete iron-chelating siderophores as virulence
factors in the iron-limiting environments of their vertebrate hosts to compete for ferric iron …

The mycobactin siderophore system is present in many Mycobacterium species, including
M. tuberculosis and other clinically relevant mycobacteria. This siderophore system is …

Siderophores are small iron-binding molecules secreted by bacteria to scavenge iron.
Mycobacterium tuberculosis (Mtb), the etiologic agent of tuberculosis, produces the …

The prolonged survival of Mycobacterium tuberculosis (M. tb) in the host fundamentally
depends on scavenging essential nutrients from host sources. M. tb scavenges non-heme …

Mycobacterium tuberculosis requires iron for normal growth but faces a limitation of the
metal ion due to its low solubility at biological pH and the withholding of iron by the …

Iron is an essential nutrient for most bacterial pathogens, but is restricted by the host immune
system. Mycobacterium tuberculosis (Mtb) utilizes two classes of small molecules …

Mycobacterium tuberculosis is an important pathogen of mammals that relies on 2-
hydroxyphenyloxazoline-containing siderophore molecules called mycobactins for the …