Synthesis, cytotoxicity and in silico study of some novel benzocoumarin-chalcone-bearing aryl ester derivatives and benzocoumarin-derived arylamide analogs

NA Abdul-Ridha, AD Salmaan, R Sabah… - … für Naturforschung B, 2021 - degruyter.com
The development of new prostate cancer protein receptor cytochrome P450 17A1 inhibitors
offers the possibility of generating structures of increased potency. To this end, the chalcone …

Synthesis, characterization and in silico studies of coumarin-chalcone derivatives and their cytotoxicity activity against breast cancer cells

MS Rahama, M Khairuddean, NZ Ismail… - Journal of Molecular …, 2025 - Elsevier
Breast carcinoma disease is the most common ailment affecting women globally. Despite
relentless efforts by scientists, numerous scientific strategies have been blocked by the …

Synthesis and anticancer activities of some new coumarin derivatives including the triazole ring and their in silico molecular docking studies

E Menteşe, A Güner, E Polatlı, M Emirik… - Archiv der …, 2021 - Wiley Online Library
The synthesis, docking study, and investigation of the anticancer activities of some coumarin
derivatives containing the triazole ring are reported in this study. The newly synthesized …

Synthesis, in vitro antiproliferative activity, and in silico studies of fused tricyclic coumarin sulfonate derivatives

MI El-Gamal, CH Oh - European Journal of Medicinal Chemistry, 2014 - Elsevier
A series of fused tricyclic coumarin sulfonate derivatives was synthesized. Their in vitro
antiproliferative activities against a panel of 57 human cancer cell lines of nine different …

Synthesis and biological evaluation of new coumarin derivatives as cytotoxic agents

FA Ragab, AAM Eissa, SH Fahim… - Archiv der …, 2021 - Wiley Online Library
New coumarin derivatives 9a–f, 10a–e, and 11a–f were synthesized and evaluated for their
cytotoxic activity against a human breast cancer cell line (MCF‐7). All compounds exhibited …

[HTML][HTML] Synthesis, molecular modeling and anticancer activity of new coumarin containing compounds

SA Morsy, AA Farahat, MNA Nasr… - Saudi Pharmaceutical …, 2017 - Elsevier
A series of new coumarin containing compounds were synthesized from 4-
bromomethylcoumarin derivatives 2a, b and different heteroaromatic systems 4a-e, 6a-d, 8 …

Synthesis, computational study and cytotoxic activity of new 4-hydroxycoumarin derivatives

S Stanchev, G Momekov, F Jensen… - European journal of …, 2008 - Elsevier
Six new 4-hydroxycoumarin derivatives have been synthesized. They were characterized by
UV–vis, IR, 1H NMR, 13C NMR, mass spectral data, elemental analysis, TLC and melting …

Synthesis of novel building blocks of benzosuberone bearing coumarin moieties and their evaluation as potential anticancer agents

B Yadagiri, UD Holagunda, R Bantu… - European Journal of …, 2014 - Elsevier
A series of novel benzosuberone bearing coumarin moieties 5a–c have been synthesized
and their structures were determined by analytical and spectral (FT-IR, 1 H NMR, 13 C NMR …

Synthesis, computational study and cytotoxicity of 4-hydroxycoumarin-derived imines/enamines

S Vaseghi, M Yousefi, M Shokrzadeh, Z Hossaini… - Molecular Diversity, 2021 - Springer
In this study, we applied a direct condensation between 3-acetyl-4-hydroxy-2 H-chromen-2-
one and different amines (anilines and benzyl amines) in order to synthesize some …

Synthesis, Cytotoxic Evaluation, and In Silico Studies of 4‐Substituted Coumarins

P Kaur, RK Gill, G Singh… - Journal of Heterocyclic …, 2016 - Wiley Online Library
Two series of coumarins possessing the aniline‐and heterocyclic ring at 4th position have
been synthesized and evaluated for their in vitro cytotoxic activity against MCF‐7 cancer cell …