Benchmarking hybrid assemblies of Giardia and prediction of widespread intra-isolate structural variation

SMJ Pollo, SJ Reiling, J Wit, ML Workentine, RA Guy… - Parasites & vectors, 2020 - Springer
Background Currently available short read genome assemblies of the tetraploid protozoan
parasite Giardia intestinalis are highly fragmented, highlighting the need for improved …

Genome analysis and comparative genomics of a Giardia intestinalis assemblage E isolate

J Jerlström-Hultqvist, O Franzén, J Ankarklev, F Xu… - BMC genomics, 2010 - Springer
Background Giardia intestinalis is a protozoan parasite that causes diarrhea in a wide range
of mammalian species. To further understand the genetic diversity between the Giardia …

Highly contiguous genomes of human clinical isolates of Giardia duodenalis reveal assemblage- and sub-assemblage-specific presence–absence variation in …

C Klotz, MW Schmid, K Winter, R Ignatius… - Microbial …, 2023 - microbiologyresearch.org
Giardia duodenalis (syn. G. intestinalis, G. lamblia) is a widespread gastrointestinal
protozoan parasite with debated taxonomic status. Currently, eight distinct genetic sub …

A novel high-resolution multilocus sequence typing of Giardia intestinalis Assemblage A isolates reveals zoonotic transmission, clonal outbreaks and recombination

J Ankarklev, M Lebbad, E Einarsson, O Franzén… - Infection, Genetics and …, 2018 - Elsevier
Molecular epidemiology and genotyping studies of the parasitic protozoan Giardia
intestinalis have proven difficult due to multiple factors, such as low discriminatory power in …

Draft Genome Sequencing of Giardia intestinalis Assemblage B Isolate GS: Is Human Giardiasis Caused by Two Different Species?

O Franzen, J Jerlström-Hultqvist, E Castro… - PLoS …, 2009 - journals.plos.org
Giardia intestinalis is a major cause of diarrheal disease worldwide and two major Giardia
genotypes, assemblages A and B, infect humans. The genome of assemblage A parasite …

Transcriptome Profiling of Giardia intestinalis Using Strand-specific RNA-Seq

O Franzén, J Jerlström-Hultqvist… - PLoS computational …, 2013 - journals.plos.org
Giardia intestinalis is a common cause of diarrheal disease and it consists of eight
genetically distinct genotypes or assemblages (AH). Only assemblages A and B infect …

A hybrid sequencing and assembly strategy for generating culture free Giardia genomes

JG Maloney, A Molokin, G Solano-Aguilar… - Current Research in …, 2022 - Elsevier
Giardia duodenalis is a pathogenic intestinal protozoan parasite of humans and many other
animals. Giardia duodenalis is found throughout the world, and infection is known to have …

Hidden diversity within common protozoan parasites as revealed by a novel genomotyping scheme

MH Seabolt, KT Konstantinidis… - Applied and …, 2021 - Am Soc Microbiol
Giardia duodenalis (syn. Giardia lamblia, Giardia intestinalis) is the causative agent of
giardiasis, one of the most common diarrheal infections in humans. Evolutionary …

Comparative genomic analyses of freshly isolated Giardia intestinalis assemblage A isolates

J Ankarklev, O Franzén, D Peirasmaki… - BMC genomics, 2015 - Springer
Background The diarrhea-causing protozoan Giardia intestinalis makes up a species
complex of eight different assemblages (AH), where assemblage A and B infect humans …

Quantitative proteomic analysis of Giardia duodenalis assemblage A: A baseline for host, assemblage, and isolate variation

SJ Emery, E Lacey, PA Haynes - Proteomics, 2015 - Wiley Online Library
Giardia duodenalis is a gastrointestinal protozoan parasite of vertebrates and is a species
complex comprised of eight assemblages, with the zoonotic assemblage A one of two …