Genome‐wide mapping of transcription factor binding reveals developmental process integration and a fresh look at evolutionary dynamics

L Yant - American Journal of Botany, 2012 - Wiley Online Library
How does evolution forge adaptive responses? Are many changes required or few? Just
how complex are the transcriptional networks that control development? Diverse questions …

Enhanced maps of transcription factor binding sites improve regulatory networks learned from accessible chromatin data

SR Kulkarni, DM Jones, K Vandepoele - Plant physiology, 2019 - academic.oup.com
Determining where transcription factors (TFs) bind in genomes provides insight into which
transcriptional programs are active across organs, tissue types, and environmental …

The end of innocence: flowering networks explode in complexity

D Posé, L Yant, M Schmid - Current opinion in plant biology, 2012 - Elsevier
Substantial recent advances in genome-scale transcription factor target mapping have
provided a fresh view of the gene networks governing developmental transitions. In …

From milliseconds to lifetimes: tracking the dynamic behavior of transcription factors in gene networks

Y Li, K Varala, GM Coruzzi - Trends in Genetics, 2015 - cell.com
Modeling dynamic gene regulatory networks (GRNs) is a new frontier in systems biology. It
has special implications for plants, whose survival requires rapid deployment of GRNs in …

ConnecTF: A platform to integrate transcription factor–gene interactions and validate regulatory networks

MD Brooks, CL Juang, MS Katari, JM Alvarez… - Plant …, 2021 - academic.oup.com
Deciphering gene regulatory networks (GRNs) is both a promise and challenge of systems
biology. The promise lies in identifying key transcription factors (TFs) that enable an …

Genome-Wide Association Mapping in Plants Exemplified for Root Growth in Arabidopsis thaliana

R Slovak, C Göschl, Ü Seren, W Busch - Plant Functional Genomics …, 2015 - Springer
Genome-wide association (GWA) mapping is a powerful technique to address the molecular
basis of genotype to phenotype relationships and to map regulators of biological processes …

From phenotypes to causal sequences: using genome wide association studies to dissect the sequence basis for variation of plant development

T Ogura, W Busch - Current opinion in plant biology, 2015 - Elsevier
Highlights•Genome Wide Association Studies (GWASs) have been conducted in 22 plant
species.•GWASs have uncovered novel mechanisms and genes underlying variation of …

Evolution of Gene Regulatory Networks in Plant Development

F Valverde, A Groover, JM Romero - Frontiers in Plant Science, 2017 - frontiersin.org
The mechanisms regulating developmental processes in plants are very sophisticated as a
result of a continuous increase in complexity during evolution. Plants undergo a wide variety …

Cooperation of gene regulatory networks and phytohormones in cell development and morphogenesis

M Asim, Y Zhang, W Liu - Frontiers in Plant Science, 2023 - frontiersin.org
The cooperation between gene regulatory networks (GRNs) and phytohormones in cell
development and morphogenesis represents a cornerstone of plant developmental biology …

Identification and evolution of gene regulatory networks: insights from comparative studies in plants

DM Jones, K Vandepoele - Current opinion in plant biology, 2020 - Elsevier
Highlights•Target genes of orthologous transcription factors can vary greatly.•Duplicated
transcription factor genes frequently have divergent expression patterns.•Comparing gene …