Natural odors, generally composed of many monomolecular components, are analyzed by
peripheral receptors into component features and translated into spatiotemporal patterns of …

Spatial and temporal activity patterns of olfactory bulb projection neurons underlie the initial
representations of odors in the brain. However, olfactory perception ultimately requires the …

Olfactory perception is initiated by the recognition of odorants by a large repertoire of
receptors in the sensory epithelium. A dispersed pattern of neural activity in the nose is …

Increased understanding of the early stages of olfaction has lead to a renewed interest in the
higher brain regions responsible for forming unified 'odor images' from the chemical …

Current models of odor discrimination in mammals involve molecular feature detection by a
large family of diverse olfactory receptors, refinement of molecular feature extraction through …

Highlights•The glomerular organization in the mammalian olfactory bulb is differentially
transformed in higher-order olfactory areas.•The microcircuitry of the piriform cortex enables …

In awake rodents, the neural representation of olfactory information in the olfactory bulb is
largely dependent on brain state and behavioral context. Learning-modified neural plasticity …

In primary sensory cortices, there are two main sources of excitation: afferent sensory input
relayed from the periphery and recurrent intracortical input. Untangling the functional roles of …

The mammalian piriform cortex receives direct synaptic input from the olfactory bulb and is
likely the locus for the formation of odor percept. It remains unclear how individual cortical …

Despite a remarkably precise spatial representation of odorant stimuli in the early stages of
olfactory processing, the projections to the olfactory (piriform) cortex are more diffuse and …