Anticalcification treatments of bioprosthetic heart valves: in vivo studies in sheep

M JONES, EE EIDBO, SL HILBERT… - Journal of Cardiac …, 1989 - Wiley Online Library
Studies performed by other investigators have shown that a number of preimplantation
processes inhibit the calcification of pieces of porcine aortic valves and of bovine parietal …

The effects of anticalcification treatments on bioprosthetic heart valves implanted in sheep.

M Jones, EE Eidbo, SL Hilbert, VJ Ferrans… - ASAIO …, 1988 - europepmc.org
Several preimplantation processes have been shown to inhibit the calcification of pieces of
porcine aortic valves and of bovine parietal pericardium implanted subcutaneously in rats …

Antimineralization treatments for bioprosthetic heart valves: assessment of efficacy and safety

FJ Schoen, RJ Levy, SL Hilbert, RW Bianco - The Journal of Thoracic and …, 1992 - Elsevier
Since calcification limits the durability of contemporary bioprosthetic heart valves,
antimineralization treatments are being widely investigated. Potential antimineralization …

Inhibition by diphosphonate compounds of calcification of porcine bioprosthetic heart valve cusps implanted subcutaneously in rats.

RJ Levy, MA Hawley, FJ Schoen, SA Lund, PY Liu - Circulation, 1985 - Am Heart Assoc
Calcification limits the long-term success of heart valve bioprostheses fabricated from
glutaraldehyde cross-linked porcine aortic valves. The pathophysiology of calcification of …

Modification by the Hancock T6 process of calcification of bioprosthetic cardiac valves implanted in sheep

E Arbustini, M Jones, RD Moses, EE Eidbo… - The American journal of …, 1984 - Elsevier
The effectiveness of the T6 process (surfactant treatment) to decrease calcification of porcine
aortic valvular (PAV) and bovine pericardial (BPV) bioprostheses was investigated …

In vitro calcification of bioprosthetic heart valves: report of a novel method and review of the biochemical factors involved.

GM Bernacca, TG Mackay… - The Journal of Heart Valve …, 1992 - europepmc.org
The lifetime of bioprosthetic heart valves is limited by primary tissue failure and calcification
of the valve leaflets. There are indications that synthetic elastomeric materials may also be …

Techniques for prevention of calcification of valvular bioprostheses.

A Carpentier, A Nashef, S Carpentier, A Ahmed… - Circulation, 1984 - europepmc.org
Calcification of valvular bioprostheses in children is a major problem that has stimulated
extensive research in our laboratory. In previous reports, we have shown that the rate of …

Onset and progression of experimental bioprosthetic heart valve calcification.

FJ Schoen, RJ Levy, AC Nelson… - … ; a journal of technical …, 1985 - europepmc.org
Calcification, the major cause of bioprosthetic heart valve failures, is a serious clinical
problem with uncertain pathogenesis. The objectives of the present study were to define the …

Prevention of calcification of heart valve bioprostheses: An experimental study in rat

J Chanda - The Annals of thoracic surgery, 1995 - Elsevier
To eliminate highly antigenic substances, bovine pericardium was washed in 5% sodium
chloride (NaCl) for 24 hours, followed by incubation in trypsin for 40 minutes. To achieve …

Current progress in anticalcif ication for bioprosthetic and polymeric heart valves

NR Vyavahare, W Chen, RR Joshi, CH Lee… - Cardiovascular …, 1997 - Elsevier
The use of bioprosthetic valves fabricated from fixed heterograft tissue (porcine aortic valves
or bovine pericardium) in heart valve replacement surgery is limited because of calcification …