Dynamic modeling of miRNA-mediated feed-forward loops
F Eduati, B Di Camillo, M Karbiener… - Journal of …, 2012 - liebertpub.com
Given the important role of microRNAs (miRNAs) in genome-wide regulation of gene
expression, increasing interest is devoted to mixed transcriptional and post-transcriptional …
expression, increasing interest is devoted to mixed transcriptional and post-transcriptional …
CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
Abstract Background Transcription Factors (TFs) and microRNAs (miRNAs) are key players
for gene expression regulation in higher eukaryotes. In the last years, a large amount of …
for gene expression regulation in higher eukaryotes. In the last years, a large amount of …
Transcription factor and microRNA co-regulatory loops: important regulatory motifs in biological processes and diseases
Transcription factors (TFs) and microRNAs (miRNAs) can jointly regulate target gene
expression in the forms of feed-forward loops (FFLs) or feedback loops (FBLs). These …
expression in the forms of feed-forward loops (FFLs) or feedback loops (FBLs). These …
From miRNA regulation to miRNA–TF co-regulation: computational approaches and challenges
Abstract microRNAs (miRNAs) are important gene regulators. They control a wide range of
biological processes and are involved in several types of cancers. Thus, exploring miRNA …
biological processes and are involved in several types of cancers. Thus, exploring miRNA …
Data integration in functional analysis of microRNAs
H Ogul, MS Akkaya - Current Bioinformatics, 2011 - ingentaconnect.com
The discovery of microRNAs (miRNAs), about a decade ago, has completely changed our
understanding of the complexity of gene regulatory networks. It has already been shown that …
understanding of the complexity of gene regulatory networks. It has already been shown that …
Analyzing miRNA co-expression networks to explore TF-miRNA regulation
S Bandyopadhyay, M Bhattacharyya - BMC bioinformatics, 2009 - Springer
Abstract Background Current microRNA (miRNA) research in progress has engendered
rapid accumulation of expression data evolving from microarray experiments. Such …
rapid accumulation of expression data evolving from microarray experiments. Such …
Analysis of miRNA, mRNA, and TF interactions through network-based methods
Recent findings have elucidated that the regulation of messenger RNA (mRNA) levels is due
to the synergistic and antagonist actions of transcription factors (TFs) and microRNAs …
to the synergistic and antagonist actions of transcription factors (TFs) and microRNAs …
A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions
JC Engelmann, R Spang - PloS one, 2012 - journals.plos.org
microRNAs (miRNAs) are short non-coding RNAs with regulatory functions in various
biological processes including cell differentiation, development and oncogenic …
biological processes including cell differentiation, development and oncogenic …
[HTML][HTML] Where we stand, where we are moving: surveying computational techniques for identifying miRNA genes and uncovering their regulatory role
Traditional biology was forced to restate some of its principles when the microRNA (miRNA)
genes and their regulatory role were firstly discovered. Typically, miRNAs are small non …
genes and their regulatory role were firstly discovered. Typically, miRNAs are small non …
Computational Methods for Identifying MicroRNA-Gene Regulatory Modules
Y Liu - Handbook of Statistical Bioinformatics, 2022 - Springer
MicroRNAs (miRNAs) are small noncoding RNA molecules that participate in post-
transcriptional gene regulation through mRNA degradation or protein translational …
transcriptional gene regulation through mRNA degradation or protein translational …