Degradation of cellulose is of major interest in the quest for alternative sources of renewable
energy, for its positive effects on environment and ecology, and for use in advanced …

Background Select cellulolytic bacteria produce multi-enzymatic cellulosome complexes that
bind to the plant cell wall and catalyze its efficient degradation. The multi-modular …

We have been developing the cellulases of Thermobifida fusca as a model to explore the
conversion from a free cellulase system to the cellulosomal mode. Three of the six T. fusca …

During the past several years, major progress has been accomplished in the production of
“designer cellulosomes,” artificial enzymatic complexes that were demonstrated to efficiently …

Lignocellulosic biomass, the most abundant polymer on Earth, is typically composed of three
major constituents: cellulose, hemicellulose, and lignin. The crystallinity of cellulose …

Cellulose deconstruction can be achieved by three distinct enzymatic paradigms: free
enzymes, multifunctional enzymes, and self‐assembled, multi‐enzyme complexes …

Cellulosomes are synthesized by anaerobic bacteria and fungi to degrade lignocellulose via
synergistic action of multiple enzymes fused to a protein scaffold. Through templating key …

Designer cellulosomes are precision-engineered multienzyme complexes in which the
molecular architecture and enzyme content are exquisitely controlled. This system was used …

Cellulosomes are efficient cellulose-degradation systems produced by selected anaerobic
bacteria. This multi-enzyme complex is assembled from a group of cellulases attached to a …

During the course of our studies on the structure–function relationship of cellulosomes, we
were interested in converting the free cellulase system of the aerobic bacterium …