The quest of man for sexual rejuvenation dates back to ancient times. In the first century AD
the ingestion of gonads was recommended as an aphrodisiac by Mesue, and for many …

Testosterone is the only androgenic substance which the biochemists have succeeded in
extracting, isolating from concentrates, and recrystallizing in a chemically pure state, from …

CLINICAL experience with the male sex hormones or androgens as substi-tute therapy for
hypogonadism has received attention in only a few reports, and these mostly during the past …

SINCE testosterone, considered to be the natural hormone of the testes, was prepared
synthetically from cholesterol by Ruzicka and Wettstein (1935) and by Butenandt and …

CLINICAL USE OF TESTOSTERONE PROPIONATE 1267 time until April 1939 he received
50 mg. 3 times weekly. During April 1939 the left testis at times descended into the scrotum; …

This study of the problem of hypogonadism in the male is presented chiefly from a clinical
point of view. The physiologic and biochemical work has been carried on under the direction …

Testicular function is known to be intimately connected with the growth of the penis and its
erectile power, the growth and maintenance of the secondary sex glands, the maturation of …

Attempts at therapeutic administration of the male hormone to man perhaps logically date
from the unsubstantiated assertions of Brown-Séquard 1 that a glycerin-water extract of …

Although the testicle actually is the first organ which was shown by experimentation to
possess an internal-secreting action through the very clear-cut transplantation studies on …

The general effects of castration, in addition to the loss of spermatogenesis, have been
known since our earliest historical records. It is not the purpose of this paper to review the …