HIVprotI: an integrated web based platform for prediction and design of HIV proteins inhibitors
A number of anti-retroviral drugs are being used for treating Human Immunodeficiency Virus
(HIV) infection. Due to emergence of drug resistant strains, there is a constant quest to …
(HIV) infection. Due to emergence of drug resistant strains, there is a constant quest to …
Investigation of novel indole-based HIV-1 protease inhibitors using virtual screening and text mining
K Sahin - Journal of Biomolecular Structure and Dynamics, 2021 - Taylor & Francis
Human immunodeficiency virus type 1 protease (HIV-1 PR) inhibitors have been used as
possible therapeutic agents for HIV-1 infection in clinical study. Most of the HIV therapy …
possible therapeutic agents for HIV-1 infection in clinical study. Most of the HIV therapy …
In silico screening of indinavir-based compounds targeting proteolytic activity in HIV PR: binding pocket fit approach
The intense research on small molecule inhibitors of Human immunodeficiency virus (HIV)-
protease (PR) has produced a diverse class of chemical scaffolds which includes clinically …
protease (PR) has produced a diverse class of chemical scaffolds which includes clinically …
Discovery of novel HIV protease inhibitors using modern computational techniques
SN Okafor, P Angsantikul, H Ahmed - International Journal of Molecular …, 2022 - mdpi.com
The human immunodeficiency virus type 1 (HIV-1) has continued to be a global concern.
With the new HIV incidence, the emergence of multi-drug resistance and the untoward side …
With the new HIV incidence, the emergence of multi-drug resistance and the untoward side …
Chemical structure and correlation analysis of HIV-1 NNRT and NRT inhibitors and database-curated, published inhibition constants with chemical structure in diverse …
B Viira, AT Garcia-Sosa, U Maran - Journal of Molecular Graphics and …, 2017 - Elsevier
Abstract Human immunodeficiency virus (HIV-1) reverse transcriptase is a major target for
designing anti-HIV drugs. Developed inhibitors are divided into non-nucleoside analog …
designing anti-HIV drugs. Developed inhibitors are divided into non-nucleoside analog …
AntiHIV-Pred: web-resource for in silico prediction of anti-HIV/AIDS activity
L Stolbov, D Druzhilovskiy, A Rudik, D Filimonov… - …, 2020 - academic.oup.com
Motivation Identification of new molecules promising for treatment of HIV-infection and HIV-
associated disorders remains an important task in order to provide safer and more effective …
associated disorders remains an important task in order to provide safer and more effective …
Exploration of the structural requirements of HIV-protease inhibitors using pharmacophore, virtual screening and molecular docking approaches for lead identification
Pharmacoinformatics approaches are widely used in the field of drug discovery as it saves
time, investment and animal sacrifice. In the present study, pharmacore-based virtual …
time, investment and animal sacrifice. In the present study, pharmacore-based virtual …
A ligand-based approach for the in silico discovery of multi-target inhibitors for proteins associated with HIV infection
A Speck-Planche, VV Kleandrova, F Luan… - Molecular …, 2012 - pubs.rsc.org
Acquired immunodeficiency syndrome (AIDS) is a dangerous disease, which damages the
immune system cells to the point that the immune system can no longer fight against other …
immune system cells to the point that the immune system can no longer fight against other …
Structural requirements for potential HIV-integrase inhibitors identified using pharmacophore-based virtual screening and molecular dynamics studies
Acquired immunodeficiency syndrome (AIDS) is a life-threatening disease which is a
collection of symptoms and infections caused by a retrovirus, human immunodeficiency virus …
collection of symptoms and infections caused by a retrovirus, human immunodeficiency virus …
Chemometric classification of HIV‐1 protease inhibitors
LJO Figueiredo, OAC Antunes - International Journal of …, 2000 - Wiley Online Library
This work presents a chemometric classification for a set of 24 known HIV‐1 protease
inhibitors, based on two pattern recognition methods widely used in quantitative structure …
inhibitors, based on two pattern recognition methods widely used in quantitative structure …