Direct local delivery of immunogenic cell death (ICD) inducers to a tumor site is an attractive
approach for leading ICD effectively, due to enabling the concentrated delivery of ICD …

Immunogenic cell death (ICD) is a powerful trigger eliciting strong immune responses
against tumors. However, traditional chemoimmunotherapy (CIT) does not last long enough …

Immunogenic cell death (ICD) of tumor cells can produce plentiful tumor-associated
antigens (TAAs) and release damage-associated molecules to communicate a danger …

Chemotherapy offers a systemic cancer treatment; however, it is limited in clinical
administration due to its serious side effects. In cancer medicine, the use of nanoparticles …

In this study, dual drug-loaded nanoparticles were constructed to co-deliver low-dose
doxorubicin (DOX) and miR-200c (DOX/miR-NPs) to inhibit programmed death-1 receptor …

The purpose of this study was to evaluate the efficacy of poly (lactic-co-glycolic acid)(PLGA)-
based vaccines in breaking immunotolerance to cancer-associated self-antigens …

Previously we showed that biodegradable nanoparticles containing poly-IC or CpG
oligodeoxynucleotide (ODN) together with ovalbumin (OVA) were efficient at inducing MHC …

Biodegradable and biocompatible polymeric nanoparticles (NPs) stand out as a key tool for
improving drug bioavailability, reducing the inherent toxicity, and targeting the intended site …

The peptide vaccine clinical trials encountered limited success because of difficulties
associated with stability and delivery, resulting in inefficient antigen presentation and low …

Effective chemotherapy remains an important issue in the treatment of drug resistant cancer.
The aim of the present study was to establish novel polymeric nanoparticles composed of …