Pyrrolizidine alkaloids (PAs) are noted for their hepatotoxic, genotoxic, and carcinogenic
effects in animals and humans following metabolic activation in the liver. In this study, herbal …

Pyrrolizidine alkaloids (PAs) contamination of foodstuffs has become a topical issue in
recent years on account of its potential hepatotoxicity to consumers. This review therefore …

Incidences of human exposure to pyrrolizidine alkaloids (PAs) and their adverse effects
have previously been reported in three African countries. In view of the increasing intake of …

Ethnopharmacological relevance Herbal medicines have been used for centuries for the
management and treatment of various ailments due to the belief that they pose only little or …

The occurrence and accompanying risks of pyrrolizidine alkaloids (PAs) in Indonesian jamu
were evaluated. PAs were detected in 34 out of 35 jamu containing PA-producing …

Pyrrolizidine alkaloids (PAs) are the most common plant-derived toxins with emerging
evidence to contaminate soil, water, nearby plants and derived food products. Outbreaks of …

EFSA was asked by the European Commission to deliver a scientific opinion on the risks for
human health related to the presence of pyrrolizidine alkaloids (PA s) in honey, tea, herbal …

Pyrrolizidine alkaloids (PAs) are secondary metabolites of plants. PAs have been reported to
be hepatotoxic, mutagenic, and carcinogenic; they are a significant group of natural toxins …

Pyrrolizidine alkaloids (PA) are common plantal toxins directed against insect herbivores.
Unsaturated PAs are known to be hepatotoxic. Many of the PAs are in addition mutagenic …

Chronic and acute dietary exposure to pyrrolizidine alkaloids (PA s) was estimated in the
European population via the consumption of plant‐derived foods. This resulted in highest …