X-ray diffraction photographs have been obtained of unoriented gels of chromatin prepared
by brief digestions of rat liver nuclei with micrococcal nuclease. At low concentration (20 …

Chromatin prepared by brief digestion of nuclei with micrococcal nuclease, and extracted in
0.2 mM EDTA, appears in the electron microscope as filaments of about 100 A diameter …

Chromosomes consist of single DNA‐histone fibres (with non‐histone protein and RNA in
the active regions) that are packed by folding or coiling into fibres which can be classified …

Recently a model has been proposed for the structure of chromatin [11, based on a
repeating unit of about 200 base pairs of DNA around a core of 8 histone molecules; 2 each …

ULTRASTRUCTURE IN CHROMATIN CONTENTS Page 1 4 ULTRASTRUCTURE IN
CHROMATIN BEAL B. HVDV Division of Biology, California Institute of Technology …

Experiments have been carried out to define clearly which histone combinations can induce
a higher order structure when combined with DNA. The criterion for a higher order structure …

A model is proposed for the structure of DNA in chromatin sub-units. Each sub-unit is
proposed to contain two turns of an inner coil, with a pitch of about 40and an external …

Diffraction of x-rays from living cells, isolated nuclei, and metaphase chromosomes gives
rise to several major low angle reflections characteristic of a highly conserved pattern of …

Electron microscopic and biochemical studies demonstrate that the fundamental structure of
chromatin depleted of lysine-rich histones is composed of a flexible chain of spherical …

Conditions have been found for the isolation of rat liver nuclei which maintain chromatin in
its native state and suppresses endogenous nuclease activity. Chromatin prepared in this …