The direct actions of phencyclidine (PCP) on mammalian sarco lemma were examined by
determination of the drug's effects on the action potentials of isolated guinea-pig ventricular …

The mechanisms responsible for the positive inotropic effect of phencyclidine were studied
in isolated preparations of guinea pig and rat heart. In electrically paced left atrial muscle …

The effects of N-acetylprocainamide (NAPA) and sotalol on membrane current systems of
guinea-pig ventricular myocytes were examined and compared with those of quinidine using …

Abstract The effects of phencyclidine [1-(1-phenylcyclohexyl)-piperidine; PCP] on cardiac
action potential duration (APD) were compared to those of some of its derivatives, in strips of …

Single guinea-pig ventricular myocytes were voltage-clamped and cell length was
measured with a photodiode array. 2. Captopril (1 x 10 (-5) M) reduced both peak early …

The 1, 4-dihydropyridine (DHP) Ca2+ antagonists and agonists can inhibit a time-and
voltage-dependent, but intracellular Ca (2+)-independent transient outward K+ current (It), in …

The dihydropyridine derivatives CGP 28392 and BAY K 8644 exert a strong positive
inotropic effect in mammalian cardiac muscle, presumably by increasing Ca influx during the …

The effects of cyproheptadine were studied on cardiac Purkinje and ventricular muscle fibres
of the dog and on cells of the sinoatrial (SA) node region of rabbit hearts, by means of …

We studied the effects of dihydropyridine Ca channel ligands (DHPs), mainly nitrendipine
and Bay K8644, on whole cell and single channel Ca currents on single myocytes isolated …

We investigated the effect of phencyclidine (PCP) on the voltage-dependent K+ current in
whole cell recordings from murine thymocytes. PCP caused a dramatic, reversible and dose …