Mitochondrial oxidative phospho rylation, the center of cellular metabolism, is pivotal for the
energy production in eukaryotes. Mitochondrial oxidative phosphorylation relies on the …

Mammalian mitochondrial respiratory chain (MRC) complexes are able to associate into
quaternary structures named supercomplexes (SCs), which normally coexist with non-bound …

The mitochondrial oxidative phosphorylation system is central to cellular metabolism. It
comprises five enzymatic complexes and two mobile electron carriers that work in a …

Mitochondria are cellular organelles that harvest energy in the form of ATP through a
process termed oxidative phosphorylation (OXPHOS), which occurs via the protein …

The mitochondrial respiratory chain (MRC) is a key energy transducer in eukaryotic cells.
Four respiratory chain complexes cooperate in the transfer of electrons derived from various …

Mitochondria are recognized as the main source of ATP to meet the energy demands of the
cell. ATP production occurs by oxidative phosphorylation when electrons are transported …

Impairment of skeletal muscle function causes disabilities in elderly people. Therefore, in an
aged society, prevention and treatment of sarcopenia are important for expanding healthy …

Several studies suggest that the assembly of mitochondrial respiratory complexes into
structures known as supercomplexes (SCs) may increase the efficiency of the electron …

Mitochondrial function depends on the correct synthesis, transport, and assembly of proteins
and cofactors of the electron transport chain. The initial idea that the respiratory chain …

Highlights•Review structural studies of mitochondrial respiratory complexes (I–IV).•These
complexes couple electron transfer and proton pumping with various mechanisms.•Complex …