Crystal structure of tRNA‐guanine transglycosylase: RNA modification by base exchange.

C Romier, K Reuter, D Suck, R Ficner - The EMBO journal, 1996 - embopress.org
tRNA‐guanine transglycosylases (TGT) are enzymes involved in the modification of the
anticodon of tRNAs specific for Asn, Asp, His and Tyr, leading to the replacement of guanine …

Mutagenesis and Crystallographic Studies of Zymomonas mobilis tRNA-Guanine Transglycosylase Reveal Aspartate 102 as the Active Site Nucleophile,

C Romier, K Reuter, D Suck, R Ficner - Biochemistry, 1996 - ACS Publications
Procaryotic tRNA-guanine transglycosylase (TGT) catalyzes the posttranscriptional base
exchange of the queuine precursor 7-aminomethyl-7-deazaguanine (preQ1) with the …

Purification, crystallization, and preliminary X‐ray diffraction studies of tRNA‐guanine transglycosylase from Zymomonas mobilis

C Romier, R Ficner, K Reuter… - … : Structure, Function, and …, 1996 - Wiley Online Library
The tRNA modifying enzyme tRNA–guanine transglycosylase (Tgt) catalyzes the exchange
of guanine in the first position of the anticodon with the queuine precursor 7‐aminomethyl‐7 …

tRNA-guanine transglycosylase from Escherichia coli: Recognition of dimeric, unmodified tRNATyr

AW Curnow, GA Garcia - Biochimie, 1994 - Elsevier
In order to probe the interaction between tRNA and the tRNA hypermodifying enzyme, tRNA-
guanine transglycosylase (TGT) from Escherichia coli, we have undertaken the generation …

Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate

W Xie, X Liu, RH Huang - Nature Structural & Molecular Biology, 2003 - nature.com
Prokaryotic tRNA guanine transglycosylase (TGT) catalyzes replacement of guanine (G) by
7-aminomethyl-7-deazaguanine (PreQ1) at the wobble position of four specific tRNAs …

tRNA−Guanine Transglycosylase from Escherichia coli:  Molecular Mechanism and Role of Aspartate 89

JD Kittendorf, LM Barcomb, ST Nonekowski… - Biochemistry, 2001 - ACS Publications
The enzyme tRNA− guanine transglycosylase (TGT, EC 2.4. 2.29) catalyzes a
posttranscriptional transglycosylation reaction involved in the incorporation of the modified …

tRNA-guanine transglycosylase from Escherichia coli: Minimal tRNA structure and sequence requirements for recognition

AW Curnow, GA Garcia - Journal of Biological Chemistry, 1995 - ASBMB
Previously, we have demonstrated that the tRNA-guanine transglycosylase (TGT) from
Escherichia coli is capable of utilizing an in vitro generated minihelix consisting of the …

tRNA-guanine transglycosylase from Escherichia coli: overexpression, purification and quaternary structure

GA Garcia, KA Koch, S Chong - Journal of molecular biology, 1993 - Elsevier
Abstract tRNA-guanine transglycosylase (TGT) is the enzyme responsible for the post-
transcriptional modification of specific tRNAs (Asn, Asp, His and Tyr) with queuine. In E. coli …

A UGU sequence in the anticodon loop is a minimum requirement for recognition by Escherichia coli tRNA-guanine transglycosylase.

S Nakanishi, T Ueda, H Hori, N Yamazaki… - Journal of Biological …, 1994 - Elsevier
Escherichia coli tRNA-guanine transglycosylase is an enzyme which catalyzes replacement
of guanine (G34) of tRNA (Asp), tRNA (Asn), tRNA (His) and tRNA (Tyr) by free guanine or …

tRNA-guanine transglycosylase from Escherichia coli: gross tRNA structural requirements for recognition

AW Curnow, FL Kung, KA Koch, GA Garcia - Biochemistry, 1993 - ACS Publications
Revised Manuscript Received February 25, 1993 abstract: tRNA-guanine transglycosylase
(TGT) is the enzyme responsible for the post-transcriptional modification of specific tRNAs …