The objectives of this study were to apply a base-driven reaction to developing a new
microencapsulation technique to prepare progesterone-containing poly-d, l-lactide-co …

An ammonolysis-based microencapsulation technique useful for the preparation of
biodegradable microspheres was described in this study. A dispersed phase consisting of …

Ethyl acetate solvent evaporation and extraction processes were developed to prepare poly
(d, l-lactide-co-glycolide) microspheres. The microencapsulation processes first emulsified a …

Unwanted drug crystals often form on the surface of PLGA microspheres or in an aqueous
phase when a hydrophobic drug undergoes emulsion‐templated microencapsulation …

The objective of this study was to develop an isopropyl formate-based evaporation process
useful in producing poly-d, l-lactide-co-glycolide microspheres. Surprisingly, the evaporating …

As a non-halogenated dispersed solvent, ethyl acetate has been most commonly used for
the manufacturing of poly-d, l-lactide-co-glycolide (PLGA) microspheres. However, ethyl …

Applicability of methyl propionate to microencapsulation was evaluated with regard to
volatility, capability of forming emulsions, and their quality. An emulsion-based technique …

Purpose. To substitute dichloromethane with a safer solvent, a solvent extraction process
using methylethyl ketone (MEK) was developed to prepare poly (d, l-lactide-co-glycolide) …

The objectives of this study were to develop an ammonolysis-based microencapsulation
technique using a nonhalogenated isopropyl formate and to evaluate its feasibility in …

A new o/o/o-solvent extraction microencapsulation method based on less toxic solvents is
presented in this study. The drug is dissolved/dispersed into a poly (d, l-lactide)/or poly (d, l …