[HTML][HTML] Neuropathology of Alzheimer's disease

JA Trejo-Lopez, AT Yachnis, S Prokop - Neurotherapeutics, 2022 - Elsevier
The key pathological hallmarks—extracellular plaques and intracellular neurofibrillary
tangles (NFT)—described by Alois Alzheimer in his seminal 1907 article are still central to …

Neuropathological assessment of the Alzheimer spectrum

KA Jellinger - Journal of Neural Transmission, 2020 - Springer
Alzheimer disease (AD), the most common form of dementia globally, classically defined a
clinicopathological entity, is a heterogenous disorder with various pathobiological subtypes …

Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship

PT Nelson, H Braak… - Journal of Neuropathology …, 2009 - academic.oup.com
Amyloid plaques and neurofibrillary tangles (NFTs) are the pathological hallmarks of
Alzheimer disease (AD). There is controversy regarding the use of current diagnostic criteria …

Advances in deep neuropathological phenotyping of Alzheimer disease: past, present, and future

MN Shakir, BN Dugger - Journal of Neuropathology & …, 2022 - academic.oup.com
Alzheimer disease (AD) is a neurodegenerative disorder characterized pathologically by the
presence of neurofibrillary tangles and amyloid beta (Aβ) plaques in the brain. The disease …

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach

TJ Montine, CH Phelps, TG Beach, EH Bigio… - Acta …, 2012 - Springer
We present a practical guide for the implementation of recently revised National Institute on
Aging–Alzheimer's Association guidelines for the neuropathologic assessment of …

The development and convergence of co-pathologies in Alzheimer's disease

JL Robinson, H Richardson, SX Xie, ER Suh… - Brain, 2021 - academic.oup.com
Cerebral amyloid angiopathy (CAA), limbic-predominant age-related TDP-43
encephalopathy neuropathological change (LATE-NC) and Lewy bodies occur in the …

Alzheimer's disease including focal presentations

N Villain, B Dubois - Seminars in neurology, 2019 - thieme-connect.com
Alzheimer's disease (AD) is the commonest neurodegenerative disease and the most
frequent cause of dementia. It affects 30 million people worldwide. Current research criteria …

Neuropathological diagnostic criteria for Alzheimer's disease

S Murayama, Y Saito - 2004 - Wiley Online Library
Neuropathological diagnostic criteria for Alzheimer's disease (AD) are based on tau‐related
pathology: NFT or neuritic plaques (NP). The Consortium to Establish a Registry for …

Neuropathological criteria for the diagnosis of Alzheimer's disease

WR Markesbery - Neurobiology of aging, 1997 - Elsevier
The definitive diagnosis of Alzheimer's disease (AD) is made at autopsy by the presence of
abundant neuritic plaques (NP) and neurofibrillary tangles (NFT) in the neocortex, entorhinal …

Pathobiological subtypes of Alzheimer disease

KA Jellinger - Dementia and Geriatric Cognitive Disorders, 2021 - karger.com
Alzheimer disease (AD), the most common form of dementia, is a heterogenous disorder
with various pathobiological subtypes. In addition to the 4 major subtypes based on the …