Genome-wide and gene-based association studies of anxiety disorders in European and African American samples
Anxiety disorders (ADs) are common mental disorders caused by a combination of genetic
and environmental factors. Since ADs are highly comorbid with each other, partially due to …
and environmental factors. Since ADs are highly comorbid with each other, partially due to …
Meta-analysis of genome-wide association studies of anxiety disorders
Anxiety disorders (ADs), namely generalized AD, panic disorder and phobias, are common,
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …
Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders
M Tesfaye, P Jaholkowski, AA Shadrin… - Psychiatry and …, 2024 - Wiley Online Library
Aims Anxiety disorders are prevalent and anxiety symptoms (ANX) co‐occur with many
psychiatric disorders. We aimed to identify genomic loci associated with ANX, characterize …
psychiatric disorders. We aimed to identify genomic loci associated with ANX, characterize …
Assessment and characterization of phenotypic heterogeneity of anxiety disorders across five large cohorts
M Lee, SH Aggen, T Otowa, E Castelao… - … journal of methods …, 2016 - Wiley Online Library
To achieve sample sizes necessary for effectively conducting genome‐wide association
studies (GWASs), researchers often combine data from samples possessing multiple …
studies (GWASs), researchers often combine data from samples possessing multiple …
Reproducible genetic risk loci for anxiety: results from∼ 200,000 participants in the Million Veteran Program
Objective: Anxiety disorders are common and often disabling. The goal of this study was to
examine the genetic architecture of anxiety disorders and anxiety symptoms, which are also …
examine the genetic architecture of anxiety disorders and anxiety symptoms, which are also …
Genetic variants associated with anxiety and stress-related disorders: a genome-wide association study and mouse-model study
Importance Anxiety and stress-related disorders are among the most common mental
disorders. Although family and twin studies indicate that both genetic and environmental …
disorders. Although family and twin studies indicate that both genetic and environmental …
Gene-based analyses reveal novel genetic overlap and allelic heterogeneity across five major psychiatric disorders
Studies using genome-wide association (GWA) single nucleotide polymorphism (SNP) level
data have indicated genetic overlap across the five major disorders in the Psychiatric …
data have indicated genetic overlap across the five major disorders in the Psychiatric …
Genome‐wide association study of generalized anxiety symptoms in the Hispanic Community Health Study/Study of Latinos
Although generalized anxiety disorder (GAD) is heritable and aggregates in families, no
genomic loci associated with GAD have been reported. We aimed to discover potential loci …
genomic loci associated with GAD have been reported. We aimed to discover potential loci …
Systematic review of genome-wide association studies of anxiety disorders and neuroticism
Objectives To summarise SNP associations identified by genome-wide association studies
(GWASs) of anxiety disorders and neuroticism; to appraise the quality of individual studies …
(GWASs) of anxiety disorders and neuroticism; to appraise the quality of individual studies …
Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study
E Friligkou, S Løkhammer, B Cabrera-Mendoza… - Nature Genetics, 2024 - nature.com
We leveraged information from more than 1.2 million participants, including 97,383 cases, to
investigate the genetics of anxiety disorders across five continental groups. Through …
investigate the genetics of anxiety disorders across five continental groups. Through …