In vitro neuronal depolarization and increased synaptic activity induced by infrared neural stimulation

B Entwisle, S McMullan, P Bokiniec, S Gross… - Biomedical Optics …, 2016 - opg.optica.org
Neuronal responses to infrared neural stimulation (INS) are explored at the single cell level
using patch-clamp electrophysiology. We examined membrane and synaptic responses of …

Whole cell patch clamp for investigating the mechanisms of infrared neural stimulation

WGA Brown, K Needham… - Journal of visualized …, 2013 - pmc.ncbi.nlm.nih.gov
It has been demonstrated in recent years that pulsed, infrared laser light can be used to elicit
electrical responses in neural tissue, independent of any further modification of the target …

Combined optical and electrical stimulation of neural tissue in vivo

AR Duke, JM Cayce, JD Malphrus… - … of biomedical optics, 2009 - spiedigitallibrary.org
Low-intensity, pulsed infrared light provides a novel nerve stimulation modality that avoids
the limitations of traditional electrical methods such as necessity of contact, presence of a …

Infrared neural stimulation: a new stimulation tool for central nervous system applications

M Chernov, AW Roe - Neurophotonics, 2014 - spiedigitallibrary.org
The traditional approach to modulating brain function (in both clinical and basic science
applications) is to tap into the neural circuitry using electrical currents applied via implanted …

Excitation of primary afferent neurons by near-infrared light in vitro

EJ Katz, IK Ilev, V Krauthamer, D Weinreich - Neuroreport, 2010 - journals.lww.com
Near-infrared light therapy is an emerging neurostimulation technology, but its cellular
mechanism of action remains unresolved. Using standard intracellular recording techniques …

Peripheral nerve stimulation

VB Center - 2002 - vanderbilt.edu
Infrared light has been shown to activate peripheral nerves in vivo using pulsed laser light;
however, translation of infrared neural stimulation (INS) to the central nervous system …

Fiberoptic array for multiple channel infrared neural stimulation of the brain

MM Chernov, RM Friedman, AW Roe - Neurophotonics, 2021 - spiedigitallibrary.org
Significance: We present a new optical method for modulating cortical activity in multiple
locations and across multiple time points with high spatial and temporal precision. Our …

Application of infrared light for in vivo neural stimulation

J Wells, C Kao, ED Jansen, P Konrad… - … of biomedical optics, 2005 - spiedigitallibrary.org
A novel method for damage-free, artifact-free stimulation of neural tissue using pulsed, low-
energy infrared laser light is presented. Optical stimulation elicits compound nerve and …

Biophysical mechanisms responsible for pulsed low-level laser excitation of neural tissue

J Wells, C Kao, P Konrad… - … with tissue and …, 2006 - spiedigitallibrary.org
Background/Objective: The traditional method of stimulating neural activity has been based
on electrical methods and remains the gold standard to date despite inherent limitations. We …

Neural stimulation with optical radiation

CP Richter, AI Matic, JD Wells… - Laser & photonics …, 2011 - Wiley Online Library
This paper reviews the existing research on infrared neural stimulation, a means of
artificially stimulating neurons that has been proposed as an alternative to electrical …