Zearalenone (ZEN) is a non-steroidal estrogenic mycotoxin produced by several species of
Fusarium in cereals and agricultural products. The major ZEN metabolites are α-zearalenol …

Zearalenone (Zen) is a fusarial mycotoxin commonly found in several food commodities
worldwide. It is frequently implicated in reproductive disorders and exerts several genotoxic …

Background: SIRT1, which belongs to the Sirtuin family of NAD-dependent enzymes, plays
diverse roles in aging, metabolism, and disease biology. It could regulate cell survival and …

Abstract Sirtuin 1 (Sirt1) exerts its cardioprotective effects in various cardiovascular diseases
via multiple cellular activities. However, the therapeutic implications of Sirt1 in hypoxic …

Zearalenone (ZEA) is a nonsteroidal estrogenic mycotoxin found in several food
commodities worldwide. ZEA causes reproductive disorders, genotoxicity, and testicular …

Many recent studies have demonstrated the involvement of endoplasmic reticulum (ER)
stress in the development of cardiac diseases and have suggested that modulation of ER …

This study aimed to investigate the effects of zearalenone (ZEA) on piglet Sertoli cell (SC)-
mitochondria-associated endoplasmic reticulum (ER) membranes (MAMs) based on …

Zearalenone (ZEA) is one of the most major food contaminants in cereal crops worldwide,
risking health of both livestock and humans. This study aimed to assess the cytotoxicity and …

Sunitinib malate is a multi-targeted tyrosine kinase inhibitor used extensively for treatment of
human tumors. However, cardiovascular adverse effects of sunitinib limit its clinical use. It is …

Although it is known that the expression and activity of sirtuin 1 (SIRT1) significantly
decrease in doxorubicin (DOX)-induced cardiomyopathy, the role of interaction between …