Patients who have severe hypogonadotropic hypogonadism caused by presumed
hypothalamic disease often have a subnormal LH response to a bolus dose of …

Patients with isolated gonadotropin deficiency were studied to determine whether pulsatile
low dose gonadotropin-releasing hormone (GnRH) could induce the hormonal changes …

The effects of increasing the frequency of pulsatile GnRH administration on LH and FSH
responsiveness were studied in five GnRH-deficient men who had achieved normal sex …

The serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) responses to
the repetitive administration of synthetic gonadotropin-releasing hormone (GnRH) were …

To elucidate whether diminished pituitary gonadotropin reserve can be restored by repeated
stimulation with luteinizing-hormone-releasing hormone, plasma luteinizing hormone and …

Although differences in plasma GnRH concentrations have been identified after iv and sc
injection of this peptide, differences in pituitary LH responses to iv and sc GnRH have not …

The effect of long-term administration of gonadotropin-releasing hormone (GnRH) for
induction and maintenance of sexual maturation was characterized in 23 men with …

The treatment of hypogonadotrophic hypogonadism with gonadotrophin releasing hormone
(LHRH) has proved difficult in the past because of a progressive decline in the pituitary …

To examine the stimulus-secretion response of human pituitary gonadotrophs in vivo, we
applied a new multiple parameter deconvolution technique to analyze (1) exogenous GnRH …

Normal pituitary and gonadal function can be maintained with long term pulsatile GnRH
administration in men with idiopathic hypogonadotropic hypogonadism (IHH), and both …