Background Animal models with various combination of host-parasite have long been employed to study malaria pathogenesis. Here, we describe the combination of Plasmodium …
FG Baptista, A Pamplona, AC Pena… - Infection and …, 2010 - Am Soc Microbiol
Cerebral malaria is the most severe complication of human infection with Plasmodium falciparum. It was shown that Plasmodium berghei ANKA-induced cerebral malaria was …
In a recent Opinion article [1], White and colleagues discuss the value of the murine Plasmodium berghei ANKA model in identifying pathological processes and therapeutic …
AL Neill, NH Hunt - Parasitology, 1992 - cambridge.org
CBA/T6 and Balb/c mice inoculated with Plasmodium berghei ANKA strain (PbA) died from cerebral malaria 6–8 days post-inoculation. DBA/2J mice similarly inoculated developed a …
NJ White, GDH Turner, IM Medana, AM Dondorp… - Trends in …, 2010 - cell.com
P. berghei ANKA infection in CBA or CB57BL/6 mice is used widely as a murine 'model'of human cerebral malaria (HCM), despite markedly different histopathological features. The …
],'The value of the mouse model in identifying pathological processes or therapeutic interventions in human cerebral malaria is questionable.'Surprisingly, this conclusion was …
NH Hunt, N Manduci, CM Thumwood - Parasitology, 1993 - cambridge.org
CBA/T6 strain mice infected with Plasmodium berghei ANKA develop cerebral symptoms and die, with mononuclear cell attachment to the cerebral microvascular endothelium …
T Voza, AM Vigário, E Belnoue, AC Grüner… - Infection and …, 2005 - Am Soc Microbiol
Recent epidemiological observations suggest that clinical evolution of Plasmodium falciparum infections might be influenced by the concurrent presence of another …
L Clemmer, YC Martins, GM Zanini… - Antimicrobial agents …, 2011 - Am Soc Microbiol
The murine model of cerebral malaria (ECM) caused by Plasmodium berghei ANKA (PbA) infection in susceptible mice has been extensively used for studies of pathogenesis and …