Background: The experience of painful episodes of ill health caused by sequelae of
erythrocytes sickling, impaired blood flow, hypercoagulation and vaso-occlusion is one of …

Sickle cell disease is an inherited multisysytem disorder. Its cardinal features, chronic
haemolytic anaemia and recurrent painful episodes, relates to the presence of mutant sickle …

Background: Sickle cell anemia (SCA) is an emerging public health challenge in India as
well as globally. The WHO recognized it as a global problem since long time. In Western …

Background: Sickle cell disease (SCD) is a hereditary haemoglobinopathy characterized by
deranged haematopoiesis, and intermittent occlusion of small blood vessels. Patients can …

Background: The platelet count, prothrombin time (PT), activated partial thromboplastin time
(APTT) and D-dimer levels of patients with sickle cell disease (SCD) in steady state (32 …

Introduction: A sickle cell anaemia one of a haemoglobinopathy, which constituted as a
model for genetically inherited disorders, the course of the disease involves may crises, the …

Objectives: To determine the D-dimer levels and some hematological parameters of adult
patients with sickle cell anemia in steady state attending the hematology clinic of Ahmadu …

Background: The evidence from various studies showed that patients with sickle cell disease
(SCD) have altered components of hemostasis such as platelet function, procoagulant …

Background: Individuals with sickle cell anaemia (SCA) have lower systemic blood
pressures compared to individuals with haemoglobin Hb AA phenotype. Objective: To …

Abstract Background/Aim: Painful vaso-occlusive crisis (VOC) is the most frequent
complication of sickle cell disease. The cause of VOC is believed to be ischemic tissue injury …