Expression of antimicrobial peptides in diabetic foot ulcer

B Rivas-Santiago, V Trujillo, A Montoya… - Journal of …, 2012 - Elsevier
BACKGROUND: Foot ulcers are one of the main diabetes complications due to its high
frequency and difficulty of complete healing. There are several factors that participate in …

Differential expression of antimicrobial peptides in margins of chronic wounds

S Dressel, J Harder, J Cordes… - Experimental …, 2010 - Wiley Online Library
Please cite this paper as: Differential expression of antimicrobial peptides in margins of
chronic wounds. Experimental Dermatology 2010; 19: 628–632. Abstract: Skin wounds …

Expression of natural antimicrobial peptide β-defensin-2 and Langerhans cell accumulation in epidermis from human non-healing leg ulcers

H Galkowska, WL Olszewski… - Folia histochemica et …, 2005 - journals.viamedica.pl
Chronic wounds like venous calf and diabetic foot ulcers are frequently contaminated and
colonized by bacteria and it remains unclear whether there is sufficient expression of …

[HTML][HTML] Bioactive antimicrobial peptides as therapeutic agents for infected diabetic foot ulcers

J Da Silva, EC Leal, E Carvalho - Biomolecules, 2021 - mdpi.com
Diabetic foot ulcer (DFU) is a devastating complication, affecting around 15% of diabetic
patients and representing a leading cause of non-traumatic amputations. Notably, the risk of …

1,25-Dihydroxyvitamin D3 Induces LL-37 and HBD-2 Production in Keratinocytes from Diabetic Foot Ulcers Promoting Wound Healing: An In Vitro Model

I Gonzalez-Curiel, V Trujillo, A Montoya-Rosales… - PloS one, 2014 - journals.plos.org
Diabetic foot ulcers (DFU) are one of the most common diabetes-related cause of
hospitalization and often lead to severe infections and poor healing. It has been recently …

Expression of antimicrobial peptides in different subtypes of cutaneous lupus erythematosus

A Kreuter, M Jaouhar, M Skrygan, C Tigges… - Journal of the American …, 2011 - Elsevier
BACKGROUND: Antimicrobial peptides (AMPs) are small effector molecules of the innate
immune system with well-known antimicrobial activity. Skin infections rarely occur in patients …

Overexpressions of hBD-2, hBD-3, and hCAP18/LL-37 in gingiva of diabetics with periodontitis

D Yılmaz, GN Güncü, E Könönen, E Barış, F Çağlayan… - Immunobiology, 2015 - Elsevier
Antimicrobial peptides of the epithelium play a significant role in the innate immune
response in the oral cavity, which is constantly exposed to microbes. Type 2 diabetes …

The role of antimicrobial peptides in human skin and in skin infectious diseases

B Schittek, M Paulmann, I Senyurek… - … disorders-drug targets …, 2008 - ingentaconnect.com
Antimicrobial peptides or proteins (AMPs) represent an ancient and efficient innate defense
mechanism which protects interfaces from infection with pathogenic microorganisms. In …

Antimicrobial peptides activity in the skin

A Herman, AP Herman - Skin Research and Technology, 2019 - Wiley Online Library
This review presents the current state of knowledge regarding multifunctional role of human
skin antimicrobial peptides (AMP s), including (a) protection from microbial infection,(b) …

Saliva induces expression of antimicrobial peptides and promotes intracellular killing of bacteria in keratinocytes by epidermal growth factor receptor transactivation

T Mohanty, P Alberius, A Schmidtchen… - British Journal of …, 2017 - academic.oup.com
Background Wounds in the oral cavity, constantly exposed to both saliva and bacteria, heal
quickly without infection. Furthermore, during licking of skin wounds, saliva promotes wound …