Thiazole derivatives were shown to have toxic effects in vitro on cancer cells of different
origin and can be considered as potentially antineoplastic, but their effect on the normal …

The influence of newly synthesized thiazole derivative N-(5-benzyl-1, 3-thiazol-2-yl)-3, 5-
dimethyl-1-benzofuran-2-carboxamide on cellular ultrastructure and antioxidant system …

Background. The influence in vitro of thiazole derivative 8-methyl-2-Me-7-[trifluoromethyl-
phenylmethyl]-pyrazolo-[4, 3-e]-[1, 3]-thiazolo-[3, 2-a]-pyrimidin-4 (2H)-one (PP2) on the …

Novel and effective treatments are urgently needed for cancer, which is still the leading
cause of death in the world. Biological characteristics linked to thiazole derivatives span a …

Background. Previous studies have shown a pronounced cytotoxic effect of thiazole
derivatives in combination with polymeric carriers on tumor cells. At the same time, the …

Accepted: 20 March 2019 oxidative stress is one of the main mechanisms by which
anticancer chemotherapeutics damage normal tissues and organs. at the same time, it is an …

Thiazole derivatives have cytotoxic effects towards tumor cells, such as glioblastoma,
melanoma, leukemia and lymphoma. However, the intracellular mechanism of this action is …

Background. The article presents a study of the antioxidant defense system of the liver of rats
under the influence of thiosulfonate esters: S-ethyl-4-aminobenzenethiosulfonate (ETS), S …

State funding for the research program of the Institute of animal biology of NAAS 35.00.
02.04 F? Study of biochemical and physiological mechanisms of action of biologically active …

Derivatives of 2-amino-5-benzylthiazole are heterocyclic pharmacophores that exhibit
different pharmacological activities including anticancer action. the mechanisms of such …