Nondestructive volumetric imaging of tissue microstructure with benchtop x-ray phase-contrast tomography and critical point drying

AM Zysk, AB Garson III, Q Xu, EM Brey… - Biomedical optics …, 2012 - opg.optica.org
The in vitro investigation of many optically opaque biological microstructures requires 3D
analysis at high resolution over a large field of view. We demonstrate a new nondestructive …

Feasibility study of the 3D visualization at high resolution of intra-cranial rabbit eyes with X-ray CT phase-contrast imaging

Y Ivanishko, A Bravin, S Kovalev… - … & Visual Science, 2017 - iovs.arvojournals.org
Purpose: The intracranial three-dimensional (3D) visualization of the whole volume of the
eyeball at micrometric resolution has not been achieved yet either in clinical nor in …

Three-dimensional mouse brain cytoarchitecture revealed by laboratory-based x-ray phase-contrast tomography

M Töpperwien, M Krenkel, D Vincenz, F Stöber… - Scientific reports, 2017 - nature.com
Studies of brain cytoarchitecture in mammals are routinely performed by serial sectioning of
the specimen and staining of the sections. The procedure is labor-intensive and the 3D …

X-ray phase tomography with near-field speckles for three-dimensional virtual histology

MC Zdora, P Thibault, W Kuo, V Fernandez, H Deyhle… - Optica, 2020 - opg.optica.org
High-contrast, high-resolution imaging of biomedical specimens is indispensable for
studying organ function and pathologies. Conventional histology, the gold standard for soft …

X-ray phase-contrast microtomography of soft tissues using a compact laboratory system with two-directional sensitivity

C Navarrete-León, A Doherty, S Savvidis, MFM Gerli… - Optica, 2023 - opg.optica.org
X-ray microtomography is a nondestructive, three-dimensional inspection technique applied
across a vast range of fields and disciplines, ranging from research to industrial …

X-ray Zernike phase contrast tomography: 3D ROI visualization of mm-sized mice organ tissues down to sub-cellular components

E Longo, L Sancey, S Flenner, A Kubec… - Biomedical optics …, 2020 - opg.optica.org
Thanks to its non-invasive nature, X-ray phase contrast tomography is a very versatile
imaging tool for biomedical studies. In contrast, histology is a well-established method …

Fast compressive lens-free tomography for 3D biological cell culture imaging

Z Luo, A Yurt, R Stahl, MS Carlon, AS Ramalho… - Optics …, 2020 - opg.optica.org
We present a compressive lens-free technique that performs tomographic imaging across a
cubic millimeter-scale volume from highly sparse data. Compared with existing lens-free 3D …

X-ray phase microtomography with a single grating for high-throughput investigations of biological tissue

MC Zdora, J Vila-Comamala, G Schulz… - Biomedical optics …, 2017 - opg.optica.org
The high-throughput 3D visualisation of biological specimens is essential for studying
diseases and developmental disorders. It requires imaging methods that deliver high …

[PDF][PDF] Three-dimensional intracellular optical<? A3B2 show [pmg: line-break justify=" yes"/]?> coherence phase imaging

F Helderman, B Haslam, JF de Boer, M de Groot - Optics Letters, 2013 - Citeseer
Quantitative phase imaging has many applications for label-free studies of the nanoscale
structure and dynamics of cells and tissues. It has been demonstrated that optical coherence …

Plastinated tissue samples as three-dimensional models for optical instrument characterization

DL Marks, EJ Chaney, SA Boppart - Optics express, 2008 - opg.optica.org
Histology of biological specimens is largely limited to investigating two-dimensional
structure because of the sectioning required to produce optically thin samples for …