PARP14 is a mono–ADP-ribosyl transferase involved in the control of immunity,
transcription, and DNA replication stress management. However, little is known about the …

ADP-ribosylation controls many processes, including transcription, DNA repair, and bacterial
toxicity. ADP-ribosyltransferases and poly-ADP-ribose polymerases (PARPs) catalyze mono …

PARP14/BAL2 is a large multidomain enzyme involved in signaling pathways with
relevance to cancer, inflammation, and infection. Inhibition of its mono-ADP-ribosylating …

ADP‐ribosylation is the addition of one or more (up to some hundreds) ADP‐ribose moieties
to acceptor proteins. There are two major families of enzymes that catalyse this reaction …

Poly (ADP-ribose) polymerase 14 (PARP14) is a member of the PARP family of enzymes
that transfer ADP-ribose from NAD+ to nucleophilic amino acids on target proteins, a …

The mammalian poly (ADP-ribose) polymerase (PARP) family includes ADP-
ribosyltransferases with diphtheria toxin homology (ARTD). Most members have mono-ADP …

Poly (ADP-ribose) polymerase 7 (PARP-7) has emerged as a critically important member of
a large enzyme family that catalyzes ADP-ribosylation in mammalian cells. PARP-7 is a …

PARP-catalysed ADP-ribosylation (ADPr) is important in regulating various cellular
pathways. Until recently, PARP-dependent mono-ADP-ribosylation has been poorly …

Abstract Poly (ADP-ribose) polymerases (PARPs) act as DNA break sensors and catalyze
the synthesis of polymers of ADP-ribose (PAR) covalently attached to acceptor proteins at …

Poly-adenosine diphosphate-ribose polymerases (PARPs) promote ADP-ribosylation, a
highly conserved, fundamental posttranslational modification (PTM). PARP catalytic …